Cell Stem Cell
Volume 24, Issue 3, 7 March 2019, Pages 363-375.e9
ArticleCholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer’s Disease Neurons
Under a Creative Commons license
open access
Graphical Abstract
Keywords
Alzheimer’s disease
induced pluripotent stem cells
disease modeling
drug screening
lipids
cholesterol metabolism
cholesteryl esters
CYP46A1 Tau
amyloid beta
proteostasis
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© 2018 The Authors. Published by Elsevier Inc.