ReviewAcute-on-chronic liver failure: Definitions, pathophysiology and principles of treatment
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open access
Keywords
Acute decompensation
Multiorgan failure
Inflammatory response
Bacterial infections
Bacterial translocation
Sterile inflammation
Immunopathology
Metabolism
Abbreviations
AARC
APASL ACLF Research Consortium
ACLF
acute-on-chronic liver failure
AKI
acute kidney injury
APASL
Asian Pacific Association for the Study of the Liver
CLIF
Chronic Liver Failure-Consortium
COSSH
Chinese Group on the Study of Severe Hepatitis
DAMPs
damage-associated molecular patterns
EASL
European Association for the Study of the Liver - Chronic Liver
ER
endoplasmic reticulum
HMGB1
high mobility group box 1
ICU
intensive care unit
INR
international normalised ratio
MELD
model for end-stage liver disease
NACSELD
North American Consortium for the Study of End-stage Liver Disease
NO
nitric oxide
OF
organ failure
PAMPs
pathogen-associated molecular patterns
PRR
pattern-recognition receptors
TLR
Toll-like receptor
UNOS
United Network for Organ Sharing
Cited by (0)
Author names in bold designate shared co-first authorship.
- †
Co-first authors.
© 2020 The Authors. Published by Elsevier B.V. on behalf of European Association for the Study of the Liver (EASL).