Current BiologyVolume 30, Issue 5, 9 March 2020, Pages R222-R224DispatchCancer Mutations: Molecular MEKanismsAuthor links open overlay panelLee BardwellShow moreShareCitehttps://doi.org/10.1016/j.cub.2020.01.039Get rights and contentUnder an Elsevier user licenseopen archiveSummaryMEK, a central component of the Ras/MAPK cascade, is mutated in human tumors and developmental disorders. Recent studies are beginning to dissect the mechanisms that make these MEK mutants hyperactive.Previous article in issueNext article in issueRecommended articlesCited by (0)© 2020 Elsevier Ltd.