Cell
Volume 143, Issue 2, 15 October 2010, Pages 225-237
ArticleThe Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove
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Graphical Abstract
Highlights
► The 50 kDa NMR structure of the two dsRBMs of ADAR2 bound to a 71 nt RNA ► Shape and sequence recognition of dsRNA by ADAR2 dsRBMs ► Importance of base-specific contacts for accurate substrate selection by ADAR2 ► Other dsRBMs may operate as sequence-specific RNA binding modules
RNA
PROTEINS
Cited by (0)
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These authors contributed equally to this work
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Present address: Department of Bioengineering, Stanford University, 318 Campus Drive, Stanford, CA 94305, USA
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Present address: Departement de Chimie Moleculaire, 38041 Grenoble Cedex09, France
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