Cell
Volume 142, Issue 3, 6 August 2010, Pages 420-432
ArticleA Minimal Midzone Protein Module Controls Formation and Length of Antiparallel Microtubule Overlaps
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Graphical Abstract
Highlights
► PRC1 autonomously recognizes antiparallel microtubule overlaps ► PRC1 recruits kinesin-4 to antiparallel microtubule overlaps ► Kinesin-4 locally inhibits microtubule growth in antiparallel overlaps ► PRC1 and kinesin-4 generate a “minimal midzone” with controlled length in vitro
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Present address: Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA
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