Cell
Volume 131, Issue 6, 14 December 2007, Pages 1047-1058
Journal home page for Cell

Review
Calcium Signaling

https://doi.org/10.1016/j.cell.2007.11.028Get rights and content
Under an Elsevier user license
open archive

Calcium ions (Ca2+) impact nearly every aspect of cellular life. This review examines the principles of Ca2+ signaling, from changes in protein conformations driven by Ca2+ to the mechanisms that control Ca2+ levels in the cytoplasm and organelles. Also discussed is the highly localized nature of Ca2+-mediated signal transduction and its specific roles in excitability, exocytosis, motility, apoptosis, and transcription.

Cited by (0)