Formation of myeloid bodies in rat liver lysosomes after chloroquine administration
References (26)
- et al.
Lysosomal changes associated with hyperoxia in the isolated perfused rat liver
Exptl. Mol. Pathol
(1968) - et al.
Uptake of dyes and drugs by living cells in culture
Life Sciences
(1964) Electron microscopy of Gaucher cells
Exptl. Mol. Pathol.
(1964)- et al.
Hydrolysis of phospholipids by a lysosomal enzyme
J. Lipid Res.
(1967) - et al.
Hepatic response to lysosomal effects of hypoxia, neutral red and chloroquine
Nature
(1967) - et al.
Histochemistry of lysosomes in rat heart muscle
J. Histochem. Cytochem.
(1967) - et al.
Histochemical methods for acid phosphatase using hexazonium pararosaniline as coupler
J. Histochem. Cytochem.
(1962) - et al.
Propylene and ethylene glycol as solvents for Sudan IV and Sudan black B
Stain Technol.
(1951) - et al.
Functions of lysosomes
Ann. Rev. Physiol.
(1966) Effect of chloroquine on morphology of cytoplasmic granules in maturing human leukocytes—an ultrastructural study
J. Clin. Invest.
(1967)
Effect of chloroquine on morphology of leukocytes and pancreatic exocrine cells from the rat
Lab. Invest.
Effects of hydroxychloroquine on the growth of mammalian cells in vitro
J. Pharmacol. Exptl. Ther.
The fixation and embedding of biological specimens
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The endosomal lipid bis(monoacylglycero) phosphate as a potential key player in the mechanism of action of chloroquine against SARS-COV-2 and other enveloped viruses hijacking the endocytic pathway
2020, BiochimieCitation Excerpt :First, phospholipid and cholesterol can reach the lysosomes either by (1) the uptake of extracellular material such as lipoproteins which enter the cell by adsorptive endocytosis [113] or surface transport [114], or by (2) interaction with intracellular membranes (autophagy) [115]. Examination of liver tissue following treatment with CQ has shown evidence for increased autophagy [116–119], and it is likely that the phospholipids that accumulate in lysosomes are mostly of intracellular origin. Secondly, phospholipid modification and degradation by lysosomal enzymes may be impaired.
Ultraviolet B radiation affects epithelial cell morphology and ultrastructure in the hepatopancreas of the freshwater decapod Macrobrachium olfersii
2020, Ecotoxicology and Environmental SafetyCitation Excerpt :Furthermore, the formation of concentric membranes in F- and R-cells was observed after UVB radiation. This form of membrane is formed by concentric multilayered lipids, and may be involved in organelle and cell membrane degeneration due to alterations in lipid bilayers caused by stressors (Abraham et al., 1968; Jao et al., 1983), or they may indicate intermediate lysosome stages, involved in autophagy. Vacuolization in the cytoplasm of F- and R-cells also observed after UVB radiation may compromise normal prawn metabolism, disturbing the synthesis and release of important molecules, such as digestive enzymes, lipoproteins, vitellogenin, hemocyanin and defenses molecules required for growth and reproduction (Subramoniam, 2011; Vogt, 1994).
Biochemical and Functional Analysis of Rat Bronchoalveolar Macrophages Containing Chemically Induced Phospholipid Inclusions
1995, Toxicology and Applied PharmacologyA new method for the investigation of endocrine-regulated autophagy and protein degradation in rat liver
1993, Experimental and Molecular PathologyAntimalarials in rheumatic diseases
1990, Bailliere's Clinical RheumatologyA review of the biology and toxicologic implications of the induction of lysosomal lamellar bodies by drugs
1989, Toxicology and Applied Pharmacology