Original PaperDepending on the stress, histone deacetylase inhibitors act as heat shock protein co-inducers in motor neurons and potentiate arimoclomol, exerting neuroprotection through multiple mechanisms in ALS models
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Keywords
Heat shock response
Motor neuron
Hsp70
HSPA1A
Histone deacetylase inhibitor
DNA repair
SOD1
FUS
HSP90 inhibitor
Amyotrophic lateral sclerosis
Motor neuron disease
Arimoclomol
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