Abstract
Determining the function of all mammalian genes remains a major challenge for the biomedical science community in the 21st century. The goal of the International Mouse Phenotyping Consortium (IMPC) over the next 10 years is to undertake broad-based phenotyping of 20,000 mouse genes, providing an unprecedented insight into mammalian gene function. This short article explores the drivers for large-scale mouse phenotyping and provides an overview of the aims and processes involved in IMPC mouse production and phenotyping.
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Brown, S.D.M., Moore, M.W. The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping. Mamm Genome 23, 632–640 (2012). https://doi.org/10.1007/s00335-012-9427-x
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DOI: https://doi.org/10.1007/s00335-012-9427-x