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Multielectrode Array (MEA)-Based Detection of Spontaneous Network Activity in Human iPSC-Derived Cortical Neurons

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Book cover Cell-Based Assays Using iPSCs for Drug Development and Testing

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1994))

Abstract

Multielectrode arrays enable the detection of spontaneous cellular network activity, which can be utilized for the characterization of a neuronal culture. Here, we describe the detection of spontaneous neuronal activity in iPSC-derived cortical neurons using a 24-well plate for a multiwall-MEA system.

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Correspondence to Valeria Kizner .

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Kizner, V., Fischer, S., Naujock, M. (2019). Multielectrode Array (MEA)-Based Detection of Spontaneous Network Activity in Human iPSC-Derived Cortical Neurons. In: Mandenius, CF., Ross, J. (eds) Cell-Based Assays Using iPSCs for Drug Development and Testing. Methods in Molecular Biology, vol 1994. Humana, New York, NY. https://doi.org/10.1007/978-1-4939-9477-9_19

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  • DOI: https://doi.org/10.1007/978-1-4939-9477-9_19

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-4939-9476-2

  • Online ISBN: 978-1-4939-9477-9

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