Regular ArticleThe physiology of lymphocyte migration through the single lymph node in vivo
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2019, Veterinary Clinics of North America - Food Animal PracticeCitation Excerpt :Uptake of the antigen is regulated by nonspecific recognition processes, and the resulting response, including secretion of intracellular signals, initiates the local inflammatory response. The antigen is then transported to the regional lymph node by the dendritic cell or free in the draining lymph, where it concentrates in the lymphoid regions of the node.35 Dendritic cells “digest” the protein antigen, which is then presented to T cells as short peptides.
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