Table 1.

The tumor spectrum and incidence of the different strains of F-1 mice with Tp53 mutations.

Hybrid StrainLymphoid hyperplasia/lymphomaOsteosarcomaAdenocarcinomaSpindle cell sarcoma/sarcomaAngioma/angiosarcomaSquamous carcinoma/carcinomaHemangiomaLipoma/lipomatous tumor/liposarcoma
129SL10%6%2%0%2%2%2%2%
A/J10%17%3%7%3%0%0%20%
Balb/cByJ4%11%13%4%15%6%2%0%
C3H23%8%4%4%0%0%0%0%
DBA21%4%7%0%4%0%4%4%
NOD24%16%3%8%1%1%3%0%
SWR30%20%11%4%4%8%1%0%
Average incidence of tumor types18%13%6%4%4%3%2%2%
Total tumors (n)58422114141167
  • The table presents the incidence of different tumor types produced by the R172H heterozygous F-1 mouse strains. Total tumors (n) are the total number of tumors for each tumor type across all strains.