Table 1.

Significant (padj < 0.25) negatively selected genes.

Gene symbolDetected sgRNAsGood sgRNAslog2 fold changeAdjusted P-value
Tceal122−3.40.0267
Gm1092132−2.60.0324
Gm1005833−1.20.0324
mmu-mir-466o22−2.40.0324
Vmn1r10022−2.50.0324
Cul922−4.30.0364
0610010B08Rik33−1.90.0526
Defa2522−1.50.0525
Gm1428822−4.40.0525
mmu-mir-669d22−3.50.0583
Olfr52222−2.40.0642
Mettl1022−4.90.0675
5031410I06Rik33−3.60.1235
Ccl21a33−1.30.1848
Wdr7232−2.20.1848
Hist1h2bc22−1.80.1848
Gm291332−4.40.2331
  • Genes in bold have identifiable human orthologues. The number of detected sgRNAs (library A contained three sgRNAs for each gene and four sgRNAs per miRNA) is shown. “Good” sgRNAs is the number of detected sgRNAs that were negatively selected.