Table 1.

Significant (padj < 0.25) negatively selected genes.

Gene symbol	Detected sgRNAs	Good sgRNAs	log₂ fold change	Adjusted P-value
*Tceal1*	2	2	−3.4	0.0267
Gm10921	3	2	−2.6	0.0324
Gm10058	3	3	−1.2	0.0324
mmu-mir-466o	2	2	−2.4	0.0324
Vmn1r100	2	2	−2.5	0.0324
*Cul9*	2	2	−4.3	0.0364
*0610010B08Rik*	3	3	−1.9	0.0526
*Defa25*	2	2	−1.5	0.0525
Gm14288	2	2	−4.4	0.0525
mmu-mir-669d	2	2	−3.5	0.0583
Olfr522	2	2	−2.4	0.0642
*Mettl10*	2	2	−4.9	0.0675
5031410I06Rik	3	3	−3.6	0.1235
*Ccl21a*	3	3	−1.3	0.1848
*Wdr72*	3	2	−2.2	0.1848
*Hist1h2bc*	2	2	−1.8	0.1848
Gm2913	3	2	−4.4	0.2331

Genes in bold have identifiable human orthologues. The number of detected sgRNAs (library A contained three sgRNAs for each gene and four sgRNAs per miRNA) is shown. “Good” sgRNAs is the number of detected sgRNAs that were negatively selected.