Table showing the sequenced locations and the aminoacids convered of the partially sequenced genes in our custom-designed MAPK pathway gene panel.

GeneChromosomeLocus positionAmino acid position
ARAFChrX47426003-47426252186-233
BRAFChr7140434532-140434640, 140439596-140439815, 140449044-140449156, 140449186-140449273, 140453021-140453215, 140453948-140454071, 140476652-140476772, 140476828-140476946, 140477788-140477937, 140481362-140481448454-526, 545-631, 642-667, 679-722
HRASChr11533782-533882, 534220-5343066-34, 58-91
KRASChr1225368427-25368555, 25378527-25378605, 25378635-25378758, 25380260-25380368, 25398189-253983104-66, 98-121, 132-173
MAPK1Chr2222123469-22123664, 22127153-22127280, 22142514-22142695, 22142879-22143107, 22153230-22153505, 22160105-22160333, 22161922-22162142, 22221511-2222164429-362
MAP2K1Chr156667947-66679845, 66727308-66727523, 66727541-66727651, 66728983-66729286, 66735605-66735722, 66736897-66737080, 66774071-66774222, 66777239-66777548, 66779529-66779647, 66781535-66781633, 66782015-66782132, 66782829-6678296121-356
MAP2K2Chr194090254-4090351, 4090679-4090789, 4094494-4094602, 4095288-4095521, 4097192-4097295, 4097316-4097449, 4099378-4099495, 4101127-4101237, 4101257-4101387, 4102338-4102451, 4110387-4110512, 4110586-4110696, 4117321-4117447, 4117464-411756652-85, 92-124, 149-183, 191-198, 236-246, 308-315, 323-350, 365-373, 483-493