Table 1.

Histopathological analysis of livers.

Sample nameInflammationaSteatosisbHepatocellular necrosiscHistological score (0–9)
Cnot1-LKO 13036
Cnot1-LKO 23036
Cnot1 (fl/fl) 10000
Cnot1 (fl/fl) 20000
Alb-CreERT2 10101
Alb-CreERT2 20000
  • a 0, no inflammation; 1, mild lymphocytic infiltration in the portal triad; 2, severe lymphocytic infiltration in portal triad; 3, extended infiltration of lymphocytes throughout the liver.

  • b 0, no steatosis; 1, microsteatosis; 2, microsteatosis and mild macrosteatosis; 3, severe macrosteatosis.

  • c 0, no necrosis; 1, mild necrosis; 2, moderate necrosis; 3, severe necrosis.