Patient characteristics.
| Characteristic | Number (%) | CDKL3 (−) | CDKL3 (+) | P-value |
|---|---|---|---|---|
| Gender | 0.446 | |||
| Female | 61 (40.1) | 32 (43.2) | 29 (37.2) | |
| Male | 91 (59.9) | 42 (56.8) | 49 (62.8) | |
| Age/year | 0.888 | |||
| <18 | 71 (46.7) | 35 (47.3) | 36 (46.2) | |
| ≥18 | 81 (53.3) | 39 (52.7) | 42 (53.8) | |
| Tumor site | 1a | |||
| Extremities | 148 (97.4) | 72 (97.3) | 76 (97.4) | |
| Non-extremities | 4 (2.6) | 2 (2.7) | 2 (2.6) | |
| Enneking’s surgical staging | 0.396 | |||
| I/II | 141 (92.8) | 70 (94.6) | 71 (91.0) | |
| III | 11 (7.2) | 4 (5.4) | 7 (9.0) | |
| Karnofsky performance status score | 0.726a | |||
| ≥80 | 146 (96.1) | 72 (97.3) | 74 (94.9) | |
| ≤70 | 6 (3.9) | 2 (2.7) | 4 (5.1) | |
| Neoadjuvant chemotherapy | 1b | |||
| Yes | 150 (98.7) | 73 (98.6) | 77 (91.0) | |
| No | 2 (1.3) | 1 (1.4) | 1 (9.0) | |
| Pathological subtype | 0.242 | |||
| Conventional | 136 (89.5) | 64 (86.5) | 72 (92.3) | |
| Telangiectatic | 16 (10.5) | 10 (13.5) | 6 (7.7) | |
| Surgical | 0.173 | |||
| Amputation | 47 (30.9) | 19 (25.7) | 28 (35.9) | |
| Limb salvage | 105 (69.1) | 55 (74.3) | 50 (64.1) | |
| Local recurrence | 0.851 | |||
| Yes | 38 (25.0) | 18 (24.3) | 20 (25.6) | |
| No | 114 (75.0) | 56 (75.7) | 58 (74.4) | |
| Metastasis | 0.024 | |||
| Yes | 94 (61.8) | 39 (52.7) | 55 (70.5) | |
| No | 58 (38.2) | 35 (47.3) | 23 (29.5) |