Table 1.

Infectivity of PKAc cKO sporozoites in C57BL/6 mice

ExperimentParasiteNumber of sporozoites injectedMice positive/mice injectedPrepatent period (day)
1TRAP/FlpL5,0004/43
PKAc cKO c15,0005/56
2TRAP/FlpL5,0002/23
PKAc cKO c15,0003/46
3TRAP/FlpL5,0002/23
PKAc cKO c25,0004/46
  • Mice were inoculated i.v. with PKAc cKO or TRAP/FlpL sporozoites. Blood smears were examined daily day 3 p.i., and mice were considered negative if parasites were not detected by day 30.