Table 2.

PKAc cKO merosomes have impaired infectivity in mice

ExperimentParasiteNumber of merosomes injectedMice positive/mice injectedPrepatent period (d)
1TRAP/FlpL15/55.6
PKAc cKO c110/5NA
TRAP/FlpL105/52.2
PKAc cKO c1100/5NA
2TRAP/FlpL105/52
PKAc cKO c1100/5NA
TRAP/FlpL10 mr5/52.4
PKAc cKO c110 mr0/5NA
TRAP/FlpL1005/51.4
PKAc cKO c11005/54.4
TRAP/FlpL100 mr5/51.6
PKAc cKO c1100 mr5/55.6
3TRAP/FlpL1005/51.2
PKAc cKO c11005/55.2
TRAP/FlpL100 mr5/51.4
PKAc cKO c1100 mr5/56.2
  • Swiss mice were inoculated i.v. with the indicated number of merosomes with or without mechanical rupture (mr). Blood smears were examined daily as described previously.