Table 1.

Anti-PbGAPDH epitope antibodies inhibit sporozoite liver invasion with similar efficacy as anti-P39 antibody.

Abα-KLHα-P39α-G6-1-20α-G6-41-60
Exp 15/50/50/51/5
Exp 24/52/50/50/5
Total9/102/100/101/10
% inhibition77.810088.9
  • A total of 200 P berghei salivary gland sporozoites together with 100 μg of each antibody were intravenously injected into each mouse. Prevalence of infection was determined with thin blood smears and Giemsa stain up to day 12 post-injection. % inhibition calculated relative to the α-KLH control.