Table 2.

Identified polysomal transcripts involved in mRNA translation that, compared with clk-1(qm30)+WT, are reduced in clk-1(qm30).

AccessionGene nameDescriptionlog2 fold change
Translation
 ZC434.5ears-1Glutamyl(E) amino-acyl tRNA synthetase−0.51
 F31E3.5eef-1A.1Eukaryotic translation elongation factor 1-α−0.67
 F25H5.4eef-2Eukaryotic translation elongation factor 2−0.53
 C27D11.1egl-45Eukaryotic translation initiation factor 3 subunit A−0.50
 F11A3.2eif-2BdeltaEukaryotic translation initiation factor 2B subunit Δ−0.79
 Y54E2A.11eif-3.BEukaryotic translation initiation factor 3 subunit B−0.38
 T23D8.4eif-3.CEukaryotic translation initiation factor 3 subunit C−0.43
 R11A8.6iars-1Isoleucyl(I) amino-acyl tRNA synthetase−0.26
 M110.4ifg-1Initiation factor 4G (eIF4G) family−0.43
 K10C3.5K10C3.5Orthologue of Ria1p−0.92
 R74.1lars-1Leucyl(L) amino-acyl tRNA synthetase−0.36
 C47E12.1sars-1Seryl(S) amino-acyl tRNA synthetase−0.43
 F28H1.3aars-2Alanyl(A) amino-acyl tRNA synthetase−0.46
 K08F11.3cif-1COP9/signalosome and eIF3 complex shared subunit−0.37
 Y41E3.10eef-1B.2Eukaryotic translation elongation factor−0.31
 Y37E3.10eif-2AEukaryotic initiation factor−1.06
 R08D7.3eif-3.DEukaryotic initiation factor−1.61
 Y40B1B.5eif-3.JEukaryotic initiation factor−1.24
 C17G10.9eif-3.LEukaryotic initiation factor−0.61
 C47B2.5eif-6Eukaryotic initiation factor−0.53
 T05H4.6erfa-1Eukaryotic release factor homolog−0.30
 F22B5.9fars-3Phenylalanyl(F) amino-acyl tRNA synthetase−1.65
 T10F2.1gars-1Glycyl(G) amino-acyl tRNA synthetase−0.41
 F53A2.6ife-1Initiation factor 4E (eIF4E) family−0.72
 B0348.6ife-3Initiation factor 4E (eIF4E) family−0.55
 T05G5.10iff-1Initiation factor five (eIF-5A) homolog−0.31
 Y54F10BM.2iffb-1Initiation factor five B (eIF5B)−0.75
 F57B9.6inf-1Initiation factor−0.31
 T02G5.9kars-1Lysyl(K) amino-acyl tRNA synthetase−0.30
 F58B3.5mars-1Methionyl(M) amino-acyl tRNA synthetase−0.62
 F22D6.3nars-1Asparaginyl(N) amino-acyl tRNA synthetase−0.64
 Y41E3.4qars-1Glutaminyl(Q) amino-acyl tRNA synthetase−0.43
 F26F4.10rars-1Arginyl(R) amino-acyl tRNA synthetase−0.55
 C47D12.6tars-1Threonyl(T) amino-acyl tRNA synthetase−0.44
 Y87G2A.5vrs-2Valyl(V) amino-acyl tRNA synthetase−0.41
 Y80D3A.1wars-1Tryptophanyl(W) amino-acyl tRNA synthetase−0.67
 Y105E8A.19yars-1Tyrosinyl(Y) amino-acyl tRNA synthetase−0.90
Ribosome
 Y71F9AL.13rpl-1Large ribosomal subunit L1 protein−0.53
 B0250.1rpl-2Large ribosomal subunit L2 protein−0.82
 F13B10.2rpl-3Large ribosomal subunit L3 protein−0.75
 B0041.4rpl-4Large ribosomal subunit L4 protein−0.95
 54C9.5rpl-5Large ribosomal subunit L5 protein−0.58
 R151.3rpl-6Large ribosomal subunit L6 protein−0.37
 Y24D9A.4rpl-7ALarge ribosomal subunit L7A protein−0.44
 R13A5.8rpl-9Large ribosomal subunit L9 protein−0.67
 JC8.3rpl-12Large ribosomal subunit L12 protein−0.48
 C32E8.2rpl-13Large ribosomal subunit L13 protein−0.56
 C04F12.4rpl-14Large ribosomal subunit L14 protein−0.30
 K11H12.2rpl-15Large ribosomal subunit L15 protein−0.61
 M01F1.2rpl-16Large ribosomal subunit L16 protein−0.73
 Y48G8AL.8rpl-17Large ribosomal subunit L17 protein−0.45
 Y45F10D.12rpl-18Large ribosomal subunit L18 protein−0.66
 C09D4.5rpl-19Large ribosomal subunit L18A protein−0.51
 E04A4.8rpl-20Large ribosomal subunit L20 protein−0.69
 C14B9.7rpl-21Large ribosomal subunit L18A protein−0.51
 D1007.12rpl-24.1Large ribosomal subunit L20 protein−0.51
 F28C6.7rpl-26Large ribosomal subunit L18A protein−0.29
 T24B8.1rpl-32Large ribosomal subunit L20 protein−0.26
 F37C12.4rpl-36Large ribosomal subunit L18A protein−0.39
 C26F1.9rpl-39Large ribosomal subunit L20 protein−0.98
 C09H10.2rpl-41Large ribosomal subunit L18A protein−0.41
 Y48B6A.2rpl-43Large ribosomal subunit L20 protein−0.50
 B0393.1rps-0Small ribosomal subunit S protein−0.49
 F56F3.5rps-1Small ribosomal subunit S1 protein−0.57
 C49H3.11rps-2Small ribosomal subunit S2 protein−0.50
 C23G10.3rps-3Small ribosomal subunit S3 protein−0.50
 Y43B11AR.4rps-4Small ribosomal subunit S4 protein−0.54
 T05E11.1rps-5Small ribosomal subunit S5 protein−0.45
 Y71A12B.1rps-6Small ribosomal subunit S6 protein−0.83
 ZC434.2rps-7Small ribosomal subunit S7 protein−0.39
 F40F11.1rps-11Small ribosomal subunit S11 protein−0.57
 F37C12.9rps-14Small ribosomal subunit S14 protein−0.51
 T08B2.10rps-17Small ribosomal subunit S17 protein−0.41
 Y57G11C.16rps-18Small ribosomal subunit S18 protein−0.48
 F37C12.11rps-21Small ribosomal subunit S21 protein−0.35
 F53A3.3rps-22Small ribosomal subunit S22 protein−0.44
 T07A9.11rps-24Small ribosomal subunit S24 protein−0.53
 H06I04.4ubl-1Small ribosomal subunit S27a protein−0.37
 Y62E10A.1rla-2Ribosomal protein, large subunit, acidic (P1)−0.39
 F10B5.1rpl-10Large ribosomal subunit L10 protein−0.42
 T22F3.4rpl-11.1Large ribosomal subunit L11 protein−1.26
 C27A2.2rpl-22Large ribosomal subunit L22 protein−0.47
 C03D6.8rpl-24.2Large ribosomal subunit L24 protein−0.68
 F52B5.6rpl-25.2Large ribosomal subunit L23a protein−0.82
 C53H9.1rpl-27Large ribosomal subunit L27 protein−0.52
 R11D1.8rpl-28Large ribosomal subunit L28 protein−0.65
 C42C1.14rpl-34Large ribosomal subunit L34 protein−0.53
 ZK1010.1rpl-40Large ribosomal subunit L40 protein−0.52
 C16A3.9rps-13Small ribosomal subunit S13 protein−0.57
 F36A2.6rps-15Small ribosomal subunit S15 protein−0.49
 T05F1.3rps-19Small ribosomal subunit S19 protein−0.44
 Y105E8A.16rps-20Small ribosomal subunit S20 protein−0.47
 F28D1.7rps-23Small ribosomal subunit S23 protein−0.62
 Y41D4B.5rps-28Small ribosomal subunit S28 protein−0.64
 C26F1.4rps-30Small ribosomal subunit S30 protein and ubiquitin−0.43
 F42C5.8rps-8Small ribosomal subunit S8 protein−0.70
 F40F8.10rps-9Small ribosomal subunit S9 protein−0.41
 W01D2.1W01D2.1Orthologue of human RPL37 (ribosomal protein L37)−0.41
 Y37E3.8Y37E3.8Orthologue of human RPL27A (ribosomal protein L27a)−0.40
mRNA processing
 W03H9.4cacn-1CACtiN (Drosophila cactus interacting protein) homolog−0.65
 F32B6.3F32B6.3Pre-mRNA processing factor 18−0.85
 K07C5.6K07C5.6Homologue of splicing factor SLU7−0.95
 F33A8.1let-858Similarity to eukaryotic initiation factor eIF-4 γ−0.47
 C04H5.6mog-4DEAH helicase−0.65
 EEED8.5mog-5DEAH box helicase 8−0.52
 C50C3.6prp-8Yeast PRP (splicing factor) related−0.27
 Y46G5A.4snrp-200Small nuclear ribonucleoprotein homologue−0.38
 C07E3.1stip-1Septin- and tuftelin-interacting protein homologue−0.84
 W04D2.6W04D2.6Orthologue of human RBM25−0.57
  • Highlighted in grey are the transcripts that were up-regulated in both the polysomal RNA as the total pool of RNA.