Table 2.

Profile of diazaborine-resistant mutants.

StrainInhA SNPSolid media MIC (μM)Liquid media IC90 (μM)
AN3438AN6534AN12855INH
H37Rv-LPWT12.5440.050.3
LP-AN3438-RM1I16T25340.4
LP-AN3438-RM2P151S50>2000.1
LP-AN3438-RM3D148G50>2000.1
LP-AN3438-RM4R195Q100>2000.4
LP-AN3438-RM5E219A100260.1
LP-AN3438-RM6I202T251600.2
LP-AN12855-RM1R195L3.00.4
LP-AN12855-RM2D148G0.80.3
LP-AN12855-RM3E219G4.60.1