Evolution
Comprehensive evolutionary analysis and nomenclature of plant G3BPsA thorough phylogenetic analysis of eukaryotic G3BPs (Rasputins) with a focus on plant G3BP proteins, classification into two subfamilies and a proposed systematic nomenclature.
Evolutionary association of receptor-wide amino acids with G protein–coupling selectivity in aminergic GPCRsEvolutionary analyses of aminergic G protein–coupled receptors reveal receptor-wide potential determinants of G protein–coupling selectivity.
Phylogenetic profiling resolves early emergence of PRC2 and illuminates its functional coreThis study strengthens the support for PRC2 emergence before the diversification of eukaryotes, detects a common presence of E(z) and ESC, indicating a conserved core, identifies diverse VEFS-Box Su(z)12 candidate proteins, and proposes a substrate specificity shift during E(z) evolution.
Profiles of telomeric repeats in Insecta reveal diverse forms of telomeric motifs in HymenopteransA bioinformatic pipeline for telomeric repeat motif detection was applied to 129 insect species and identified diverse forms of telomeric motifs in Hymenopterans, including canonical 5-bp, novel 8- and 9-bp forms, suggesting extraordinary evolutionary fluidity of telomeric repeat in Hymenopterans.
LINE-1 and SINE-B1 mapping and genome diversification in Proechimys species (Rodentia: Echimyidae)Signal distribution of L1 and B1 among chromosomes in five species of Proechimys may represent a strong indication of their role in karyotype diversity of this speciose Neotropical rodent.
Human BRCA pathogenic variants were originated during recent human historyEvolutionary origin of pathogenic variants in human BRCA1 and BRCA2.
Mammalian splicing divergence is shaped by drift, buffering in trans, and a scaling lawThis study globally investigates the allelic splicing pattern in multiple tissues of an F1 hybrid mouse and reveals the underlying driving forces shaping such tissue-dependent splicing divergence.
CNVs with adaptive potential in Rangifer tarandus: genome architecture and new annotated assemblyNext-generation sequencing of three caribou ecotypes aligned to a new annotated genome assembly revealed divergent CNVs, including genes with annotations in line with adaptation.
Distinct mechanisms mediate X chromosome dosage compensation in Anopheles and DrosophilaCRISPR knockout of msl-2 and epigenome analyses in Anopheles reveal that X chromosome dosage compensation in mosquitos and Drosophila is achieved by two different molecular mechanisms.
Hierarchical dinucleotide distribution in genome along evolution and its effect on chromatin packingIt describes how hierarchical CpG distribution on the genomes of species change in the evolution and the correlation with the chromatin structure.