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More articles from Resource

  • Single-cell RNA sequencing of human breast tumour-infiltrating immune cells reveals a γδ T-cell subtype associated with good clinical outcome
    Open Access
    Single-cell RNA sequencing of human breast tumour-infiltrating immune cells reveals a γδ T-cell subtype associated with good clinical outcome

    Katerina Boufea, Victor Gonzalez-Huici, Marcus Lindberg, Nelly N Olova, Stefan Symeonides, Olga Oikonomidou, Nizar N Batada

    Katerina Boufea ... Nizar N Batada

    Published 2 December 2020

    Single-cell sequencing of γδ-T cells from human blood and tumours revealed novel markers of subtypes with distinct effector functions and a subtype that is associated with favourable clinical outcome.

  • Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice
    Open Access
    Identification and characterization of distinct brown adipocyte subtypes in C57BL/6J mice

    Ruth Karlina, Dominik Lutter, Viktorian Miok, David Fischer, Irem Altun, Theresa Schöttl, Kenji Schorpp, Andreas Israel, Cheryl Cero, James W Johnson, Ingrid Kapser-Fischer, Anika Böttcher, Susanne Keipert, Annette Feuchtinger, Elisabeth Graf, Tim Strom, Axel Walch, Heiko Lickert, Thomas Walzthoeni, Matthias Heinig, Fabian J Theis, Cristina García-Cáceres, Aaron M Cypess, Siegfried Ussar

    Ruth Karlina ... Siegfried Ussar

    Published 30 November 2020

    Using a number of cell biological and statistical methods we identify and characterize EIF5, TCF25 and BIN1 as markers for individual brown adipocyte subtypes in C57BL/6J mice.

  • <em>Leishmania</em>-infected macrophages release extracellular vesicles that can promote lesion development
    Open Access
    Leishmania-infected macrophages release extracellular vesicles that can promote lesion development

    Anna Gioseffi, Tim Hamerly, Kha Van, Naixin Zhang, Rhoel R Dinglasan, Phillip A Yates, Peter E Kima

    Anna Gioseffi ... Peter E Kima

    Published 29 October 2020

    Macrophages infected with Leishmania donovani release extracellular vesicles that are composed of parasite and host-derived molecules that have the potential to induce vascular changes in tissues.

  • Genome-wide R-loop analysis defines unique roles for DDX5, XRN2, and PRMT5 in DNA/RNA hybrid resolution
    Open Access
    Genome-wide R-loop analysis defines unique roles for DDX5, XRN2, and PRMT5 in DNA/RNA hybrid resolution

    Oscar D Villarreal, Sofiane Y Mersaoui, Zhenbao Yu, Jean-Yves Masson, Stéphane Richard

    Oscar D Villarreal ... Stéphane Richard

    Published 3 August 2020

    Genome-wide analysis of R-loop alterations in U2OS cells deficient of DDX5, XRN2, and PRMT5 identify >50,650 DRIP-seq peaks spanning ∼4.5% of the genomic sequence. R-loops near TSS generated intergenic antisense transcription.

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