Plasmacytoid dendritic cell sensing of hepatitis E virus is shaped by both viral and host factors

Garima Joshi; Elodie Décembre; Jacques Brocard; Claire Montpellier; Martin Ferrié; Omran Allatif; Ann-Kathrin Mehnert; Johann Pons; Delphine Galiana; Viet Loan Dao Thi; Nolwenn Jouvenet; Laurence Cocquerel; Marlène Dreux

doi:10.26508/lsa.202503256

Research Article

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Plasmacytoid dendritic cell sensing of hepatitis E virus is shaped by both viral and host factors

View ORCID ProfileGarima Joshi Correspondence email, View ORCID ProfileElodie Décembre, Jacques Brocard, Claire Montpellier, View ORCID ProfileMartin Ferrié, View ORCID ProfileOmran Allatif, View ORCID ProfileAnn-Kathrin Mehnert, View ORCID ProfileJohann Pons, View ORCID ProfileDelphine Galiana, View ORCID ProfileViet Loan Dao Thi, View ORCID ProfileNolwenn Jouvenet, View ORCID ProfileLaurence Cocquerel, View ORCID ProfileMarlène Dreux Correspondence email

Garima Joshi

1CIRI, INSERM, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, École Normale Supérieure de Lyon, University Lyon, Lyon, France

Roles: Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing—original draft, Writing—review and editing

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ORCID record for Garima Joshi
For correspondence: garima.joshi@ens-lyon.fr

Elodie Décembre

1CIRI, INSERM, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, École Normale Supérieure de Lyon, University Lyon, Lyon, France

Roles: Investigation, Methodology

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Jacques Brocard

2Université Claude Bernard Lyon 1, CNRS UAR3444, INSERMUS8, ENS de Lyon, SFR Biosciences, Lyon, France

Roles: Formal analysis, Validation, Methodology

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Claire Montpellier

3University Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Center for Infection and Immunity of Lille, Lille, France

Roles: Resources, Investigation, Methodology

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Martin Ferrié

3University Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Center for Infection and Immunity of Lille, Lille, France

Roles: Resources, Investigation, Methodology

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Omran Allatif

1CIRI, INSERM, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, École Normale Supérieure de Lyon, University Lyon, Lyon, France

Roles: Formal analysis, Validation

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Ann-Kathrin Mehnert

5Department of Infectious Diseases, Virology, Heidelberg University, Medical Faculty Heidelberg, Heidelberg, Germany and German Centre for Infection Research (DZIF), Partner Site Heidelberg, Heidelberg, Germany

Roles: Investigation

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Johann Pons

6Sup’biotech, École Des Ingénieurs En Biotechnologies, Villejuif, Paris

Roles: Investigation

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Delphine Galiana

1CIRI, INSERM, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, École Normale Supérieure de Lyon, University Lyon, Lyon, France

Roles: Formal analysis, Supervision, Investigation, Writing—review and editing

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Viet Loan Dao Thi

Roles: Resources, Supervision, Methodology, Writing—review and editing

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Nolwenn Jouvenet

4Institut Pasteur, Université de Paris, CNRS UMR 3569, Virus sensing and signaling Unit, Paris, France

Roles: Formal analysis, Supervision, Validation, Writing—review and editing

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Laurence Cocquerel

3University Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Center for Infection and Immunity of Lille, Lille, France

Roles: Conceptualization, Resources, Formal analysis, Supervision, Validation, Methodology, Writing—review and editing

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Marlène Dreux

1CIRI, INSERM, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, École Normale Supérieure de Lyon, University Lyon, Lyon, France

Roles: Conceptualization, Supervision, Funding acquisition, Writing—original draft, Writing—review and editing

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ORCID record for Marlène Dreux
For correspondence: garima.joshi@ens-lyon.fr

Published 2 April 2025. DOI: 10.26508/lsa.202503256

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PDC’s healing touch is fundamental to fight HEV infection

Garima Joshi, Elodie Décembre, Jacques Brocard, Claire Montpellier, Martin Ferrié, Omran Allatif, Ann-Kathrin Mehnert, Johann Pons, Delphine Galiana, Viet Loan Dao Thi, Nolwenn Jouvenet, Laurence Cocquerel, Marlène Dreux

Life Science Alliance Apr 2025, 8 (6) e202503256; DOI: 10.26508/lsa.202503256

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PDC’s healing touch is fundamental to fight HEV infection

Life Science Alliance Apr 2025, 8 (6) e202503256; DOI: 10.26508/lsa.202503256

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