Antibodies targeting ADAM17 reverse neurite outgrowth inhibition by myelin-associated inhibitors

Nayanendu Saha; Eric Chan; Rachelle P Mendoza; Yevgeniy Romin; Murray J Tipping; Dimitar B Nikolov

doi:10.26508/lsa.202403126

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Antibodies targeting ADAM17 reverse neurite outgrowth inhibition by myelin-associated inhibitors

View ORCID ProfileNayanendu Saha Correspondence email, Eric Chan, Rachelle P Mendoza, Yevgeniy Romin, View ORCID ProfileMurray J Tipping, View ORCID ProfileDimitar B Nikolov Correspondence email

Nayanendu Saha

1Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA

Roles: Conceptualization, Investigation, Writing—original draft, Writing—review and editing

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ORCID record for Nayanendu Saha
For correspondence: sahan@mskcc.org

Eric Chan

2Molecular Cytology Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA

Roles: Software, Methodology

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Rachelle P Mendoza

3Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA

Roles: Software

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Yevgeniy Romin

2Molecular Cytology Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA

Roles: Methodology

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Murray J Tipping

2Molecular Cytology Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA

Roles: Supervision, Methodology

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ORCID record for Murray J Tipping

Dimitar B Nikolov

1Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA

Roles: Software, Formal analysis, Supervision, Funding acquisition, Methodology, Writing—original draft, Writing—review and editing

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ORCID record for Dimitar B Nikolov
For correspondence: nikolovd@mskcc.org

Published 25 March 2025. DOI: 10.26508/lsa.202403126

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Anti-ADAM17 antibodies reverse neurite outgrowth inhibition

Nayanendu Saha, Eric Chan, Rachelle P Mendoza, Yevgeniy Romin, Murray J Tipping, Dimitar B Nikolov

Life Science Alliance Mar 2025, 8 (6) e202403126; DOI: 10.26508/lsa.202403126

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Anti-ADAM17 antibodies reverse neurite outgrowth inhibition

Nayanendu Saha, Eric Chan, Rachelle P Mendoza, Yevgeniy Romin, Murray J Tipping, Dimitar B Nikolov

Life Science Alliance Mar 2025, 8 (6) e202403126; DOI: 10.26508/lsa.202403126

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