Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1) reveals the conformational flexibility of its lipid binding domain

Vikas Navratna; Arvind Kumar; Jaimin K Rana; Shyamal Mosalaganti

doi:10.26508/lsa.202402624

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Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1) reveals the conformational flexibility of its lipid binding domain

View ORCID ProfileVikas Navratna Correspondence email, View ORCID ProfileArvind Kumar, Jaimin K Rana, View ORCID ProfileShyamal Mosalaganti Correspondence email

Vikas Navratna

1Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA

2Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA

Roles: Conceptualization, Data curation, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Visualization, Methodology, Writing—original draft, Project administration, Writing—review and editing

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ORCID record for Vikas Navratna
For correspondence: navratna@umich.edu

Arvind Kumar

3Thermo Fisher Scientific, Waltham, MA, USA

Roles: Formal analysis, Validation, Investigation, Visualization, Writing—review and editing

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ORCID record for Arvind Kumar

Jaimin K Rana

1Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA

2Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA

Roles: Data curation, Validation, Writing—review and editing

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Shyamal Mosalaganti

1Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA

2Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA

4Department of Biophysics, College of Literature, Science and the Arts, University of Michigan, Ann Arbor, MI, USA

Roles: Conceptualization, Supervision, Funding acquisition, Visualization, Project administration, Writing—review and editing

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ORCID record for Shyamal Mosalaganti
For correspondence: mosalaga@umich.edu

Published 26 June 2024. DOI: 10.26508/lsa.202402624

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Cryo-EM structure of the apo-hSIDT1

Vikas Navratna, Arvind Kumar, Jaimin K Rana, Shyamal Mosalaganti

Life Science Alliance Jun 2024, 7 (9) e202402624; DOI: 10.26508/lsa.202402624

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Cryo-EM structure of the apo-hSIDT1

Vikas Navratna, Arvind Kumar, Jaimin K Rana, Shyamal Mosalaganti

Life Science Alliance Jun 2024, 7 (9) e202402624; DOI: 10.26508/lsa.202402624

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September 2024

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