Research Article
Open Access
DOCK1 insufficiency disrupts trophoblast function and pregnancy outcomes via DUSP4-ERK pathway
View ORCID ProfileYichi Xu, Xiaorui Liu, Weihong Zeng, Yueyue Zhu, Junpeng Dong, Fan Wu, Cailian Chen, Surendra Sharma, View ORCID ProfileYi Lin Correspondence email
Yichi Xu
1The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
2Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China
3Institute of Birth Defects and Rare Diseases, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Roles: Conceptualization, Data curation, Formal analysis, Validation, Investigation, Visualization, Methodology, Writing—original draft, Writing—review and editing
Xiaorui Liu
1The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
2Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China
3Institute of Birth Defects and Rare Diseases, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Roles: Resources, Investigation, Methodology, Project administration, Writing—review and editing
Weihong Zeng
1The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
2Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China
3Institute of Birth Defects and Rare Diseases, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Roles: Investigation, Methodology, Writing—review and editing
Yueyue Zhu
1The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
2Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China
3Institute of Birth Defects and Rare Diseases, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Roles: Validation, Investigation, Visualization, Methodology
Junpeng Dong
1The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
2Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China
3Institute of Birth Defects and Rare Diseases, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Roles: Investigation, Visualization, Methodology
Fan Wu
1The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
2Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, China
3Institute of Birth Defects and Rare Diseases, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Roles: Data curation, Formal analysis, Writing—review and editing
Cailian Chen
4Department of Automation, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai, China
5Key Laboratory of System Control and Information Processing, Ministry of Education of China, Shanghai, China
Roles: Formal analysis, Visualization, Methodology
Surendra Sharma
6Department of Pediatrics, Women and Infants Hospital of Rhode Island, Warren Alpert Medical School of Brown University, Providence, RI, USA
Roles: Conceptualization, Investigation, Writing—review and editing
Yi Lin
7Center of Reproductive Medicine, Department of Obstetrics and Gynecology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
Roles: Conceptualization, Resources, Data curation, Supervision, Funding acquisition, Methodology, Project administration, Writing—review and editing
Published 15 November 2023. DOI: 10.26508/lsa.202302247
DOCK1 & trophoblast dysfunction
Yichi Xu, Xiaorui Liu, Weihong Zeng, Yueyue Zhu, Junpeng Dong, Fan Wu, Cailian Chen, Surendra Sharma, Yi Lin
Life Science Alliance Nov 2023, 7 (2) e202302247; DOI: 10.26508/lsa.202302247
In this Issue
Volume 7, No. 2
February 2024
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