Mitochondrial apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways

Melissa Damiecki; Ritam Naha; Yulia Schaumkessel; Philipp Westhoff; Nika Atanelov; Anja Stefanski; Patrick Petzsch; Kai Stühler; Karl Köhrer; Andreas PM Weber; Ruchika Anand; Andreas S Reichert; Arun Kumar Kondadi

doi:10.26508/lsa.202403038

Research Article

Open Access

Mitochondrial apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways

View ORCID ProfileMelissa Damiecki, View ORCID ProfileRitam Naha, View ORCID ProfileYulia Schaumkessel, View ORCID ProfilePhilipp Westhoff, Nika Atanelov, View ORCID ProfileAnja Stefanski, View ORCID ProfilePatrick Petzsch, Kai Stühler, Karl Köhrer, View ORCID ProfileAndreas PM Weber, View ORCID ProfileRuchika Anand, View ORCID ProfileAndreas S Reichert, View ORCID ProfileArun Kumar Kondadi Correspondence email

Melissa Damiecki

1Institute of Biochemistry and Molecular Biology I, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Roles: Data curation, Formal analysis, Validation, Investigation, Visualization, Methodology, Writing—original draft, Writing—review and editing

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Ritam Naha

1Institute of Biochemistry and Molecular Biology I, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Roles: Formal analysis, Investigation

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Yulia Schaumkessel

1Institute of Biochemistry and Molecular Biology I, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Roles: Formal analysis, Investigation

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Philipp Westhoff

2Institute of Plant Biochemistry, Cluster of Excellence on Plant Sciences (CEPLAS), Heinrich Heine University Düsseldorf, Düsseldorf, Germany

3Plant Metabolism and Metabolomics Laboratory, Cluster of Excellence on Plant Sciences (CEPLAS), Heinrich Heine University, Düsseldorf, Germany

Roles: Formal analysis, Investigation, Methodology

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Nika Atanelov

1Institute of Biochemistry and Molecular Biology I, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Roles: Formal analysis, Investigation

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Anja Stefanski

4Molecular Proteomics Laboratory, Medical Faculty and University Hospital, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Roles: Formal analysis, Investigation, Methodology

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Patrick Petzsch

5Genomics and Transcriptomics Laboratory, BMFZ, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Roles: Formal analysis, Investigation, Methodology

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Kai Stühler

4Molecular Proteomics Laboratory, Medical Faculty and University Hospital, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

6Institute of Molecular Medicine, Protein Research, Medical Faculty and University Hospital, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Roles: Resources

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Karl Köhrer

5Genomics and Transcriptomics Laboratory, BMFZ, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Roles: Resources

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Andreas PM Weber

2Institute of Plant Biochemistry, Cluster of Excellence on Plant Sciences (CEPLAS), Heinrich Heine University Düsseldorf, Düsseldorf, Germany

3Plant Metabolism and Metabolomics Laboratory, Cluster of Excellence on Plant Sciences (CEPLAS), Heinrich Heine University, Düsseldorf, Germany

Roles: Resources, Funding acquisition

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ORCID record for Andreas PM Weber

Ruchika Anand

1Institute of Biochemistry and Molecular Biology I, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Roles: Resources, Funding acquisition, Writing—review and editing

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Andreas S Reichert

1Institute of Biochemistry and Molecular Biology I, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Roles: Conceptualization, Resources, Funding acquisition, Project administration, Writing—review and editing

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Arun Kumar Kondadi

1Institute of Biochemistry and Molecular Biology I, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

Roles: Conceptualization, Supervision, Funding acquisition, Visualization, Writing—original draft, Project administration, Writing—review and editing

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ORCID record for Arun Kumar Kondadi
For correspondence: kondadi@hhu.de

Published 11 October 2024. DOI: 10.26508/lsa.202403038

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MIC26 regulates cellular fuel pathways

Melissa Damiecki, Ritam Naha, Yulia Schaumkessel, Philipp Westhoff, Nika Atanelov, Anja Stefanski, Patrick Petzsch, Kai Stühler, Karl Köhrer, Andreas PM Weber, Ruchika Anand, Andreas S Reichert, Arun Kumar Kondadi

Life Science Alliance Oct 2024, 7 (12) e202403038; DOI: 10.26508/lsa.202403038

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MIC26 regulates cellular fuel pathways

Life Science Alliance Oct 2024, 7 (12) e202403038; DOI: 10.26508/lsa.202403038

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