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Mitochondrial double-stranded RNA homeostasis depends on cell-cycle progression

Vanessa Xavier, Silvia Martinelli, Ryan Corbyn, Rachel Pennie, Kai Rakovic, Ian R Powley, Leah Officer-Jones, View ORCID ProfileVincenzo Ruscica, View ORCID ProfileAlison Galloway, Leo M Carlin, View ORCID ProfileVictoria H Cowling, John Le Quesne, View ORCID ProfileJean-Claude Martinou  Correspondence email, View ORCID ProfileThomas MacVicar  Correspondence email
Vanessa Xavier
1The CRUK Scotland Institute, Glasgow, UK
2Department of Molecular and Cellular Biology, University of Geneva, Genève, Switzerland
Roles: Conceptualization, Formal analysis, Validation, Investigation, Visualization, Methodology, Writing—original draft, Writing—review and editing
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Silvia Martinelli
1The CRUK Scotland Institute, Glasgow, UK
3School of Cancer Sciences, University of Glasgow, Glasgow, UK
Roles: Data curation, Validation, Investigation, Methodology
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Ryan Corbyn
1The CRUK Scotland Institute, Glasgow, UK
Roles: Software, Visualization, Methodology
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Rachel Pennie
1The CRUK Scotland Institute, Glasgow, UK
3School of Cancer Sciences, University of Glasgow, Glasgow, UK
Roles: Investigation, Methodology
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Kai Rakovic
1The CRUK Scotland Institute, Glasgow, UK
3School of Cancer Sciences, University of Glasgow, Glasgow, UK
Roles: Data curation, Validation, Writing—review and editing
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Ian R Powley
1The CRUK Scotland Institute, Glasgow, UK
3School of Cancer Sciences, University of Glasgow, Glasgow, UK
Roles: Data curation, Formal analysis, Validation, Writing—review and editing
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Leah Officer-Jones
1The CRUK Scotland Institute, Glasgow, UK
3School of Cancer Sciences, University of Glasgow, Glasgow, UK
Roles: Supervision, Validation, Methodology, Writing—review and editing
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Vincenzo Ruscica
4MRC-University of Glasgow Centre for Virus Research, Glasgow, UK
Roles: Investigation, Writing—review and editing
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  • ORCID record for Vincenzo Ruscica
Alison Galloway
1The CRUK Scotland Institute, Glasgow, UK
Roles: Investigation, Writing—review and editing
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  • ORCID record for Alison Galloway
Leo M Carlin
1The CRUK Scotland Institute, Glasgow, UK
3School of Cancer Sciences, University of Glasgow, Glasgow, UK
Roles: Resources, Supervision, Writing—review and editing
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Victoria H Cowling
1The CRUK Scotland Institute, Glasgow, UK
3School of Cancer Sciences, University of Glasgow, Glasgow, UK
Roles: Supervision, Validation
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  • ORCID record for Victoria H Cowling
John Le Quesne
1The CRUK Scotland Institute, Glasgow, UK
3School of Cancer Sciences, University of Glasgow, Glasgow, UK
Roles: Resources, Supervision, Funding acquisition, Validation, Methodology
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Jean-Claude Martinou
2Department of Molecular and Cellular Biology, University of Geneva, Genève, Switzerland
Roles: Conceptualization, Resources, Supervision, Funding acquisition, Validation, Project administration, Writing—review and editing
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  • ORCID record for Jean-Claude Martinou
  • For correspondence: Jean-Claude.Martinou@unige.ch
Thomas MacVicar
1The CRUK Scotland Institute, Glasgow, UK
3School of Cancer Sciences, University of Glasgow, Glasgow, UK
Roles: Conceptualization, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Visualization, Writing—original draft, Project administration, Writing—review and editing
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  • ORCID record for Thomas MacVicar
  • For correspondence: Thomas.MacVicar@glasgow.ac.uk
Published 29 August 2024. DOI: 10.26508/lsa.202402764
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Article Information

vol. 7 no. 11 e202402764
DOI 
https://doi.org/10.26508/lsa.202402764
PubMed 
39209534

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received April 10, 2024
  • Revision received August 19, 2024
  • Accepted August 21, 2024
  • Published online August 29, 2024.

Copyright & Usage 
© 2024 Xavier et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Vanessa Xavier1,2, Conceptualization, Formal analysis, Validation, Investigation, Visualization, Methodology, Writing—original draft, Writing—review and editing,
  2. Silvia Martinelli1,3, Data curation, Validation, Investigation, Methodology,
  3. Ryan Corbyn1, Software, Visualization, Methodology,
  4. Rachel Pennie1,3, Investigation, Methodology,
  5. Kai Rakovic1,3, Data curation, Validation, Writing—review and editing,
  6. Ian R Powley1,3, Data curation, Formal analysis, Validation, Writing—review and editing,
  7. Leah Officer-Jones1,3, Supervision, Validation, Methodology, Writing—review and editing,
  8. Vincenzo Ruscica4, Investigation, Writing—review and editing,
  9. Alison Galloway1, Investigation, Writing—review and editing,
  10. Leo M Carlin1,3, Resources, Supervision, Writing—review and editing,
  11. Victoria H Cowling1,3, Supervision, Validation,
  12. John Le Quesne1,3, Resources, Supervision, Funding acquisition, Validation, Methodology,
  13. Jean-Claude Martinou2⇑, Conceptualization, Resources, Supervision, Funding acquisition, Validation, Project administration, Writing—review and editing and
  14. Thomas MacVicar1,3⇑, Conceptualization, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Visualization, Writing—original draft, Project administration, Writing—review and editing
  1. 1The CRUK Scotland Institute, Glasgow, UK
  2. 2Department of Molecular and Cellular Biology, University of Geneva, Genève, Switzerland
  3. 3School of Cancer Sciences, University of Glasgow, Glasgow, UK
  4. 4MRC-University of Glasgow Centre for Virus Research, Glasgow, UK
  1. Correspondence: Jean-Claude.Martinou{at}unige.ch
  2. Thomas.MacVicar{at}glasgow.ac.uk
View Full Text

Funding

  • Cancer Research UK (CRUK)

    RCCFELCDF-May21\100001
    T MacVicar
  • Cancer Research UK (CRUK)

    CRUK A23983
    LM Carlin
  • Cancer Research UK (CRUK)

    A17196 and A31287
    V Xavier, S Martinelli, R Corbyn, R Pennie, K Rakovic, IR Powley, L Officer-Jones, V Ruscica, A Galloway, LM Carlin, VH Cowling, J Le Quesne
  • EC | Horizon Europe | Excellent Science | HORIZON EUROPE Marie Sklodowska-Curie Actions (MSCA)

    ITN REMIX 721757
    V Xavier, J-C Martinou
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Mitochondrial dsRNA in cancer
Vanessa Xavier, Silvia Martinelli, Ryan Corbyn, Rachel Pennie, Kai Rakovic, Ian R Powley, Leah Officer-Jones, Vincenzo Ruscica, Alison Galloway, Leo M Carlin, Victoria H Cowling, John Le Quesne, Jean-Claude Martinou, Thomas MacVicar
Life Science Alliance Aug 2024, 7 (11) e202402764; DOI: 10.26508/lsa.202402764

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Mitochondrial dsRNA in cancer
Vanessa Xavier, Silvia Martinelli, Ryan Corbyn, Rachel Pennie, Kai Rakovic, Ian R Powley, Leah Officer-Jones, Vincenzo Ruscica, Alison Galloway, Leo M Carlin, Victoria H Cowling, John Le Quesne, Jean-Claude Martinou, Thomas MacVicar
Life Science Alliance Aug 2024, 7 (11) e202402764; DOI: 10.26508/lsa.202402764
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Volume 7, No. 11
November 2024
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  • Cancer
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