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Predictive data-driven modeling of C-terminal tyrosine function in the EGFR signaling network

Jacqueline S Gerritsen, Joseph S Faraguna, Rudy Bonavia, View ORCID ProfileFrank B Furnari, View ORCID ProfileForest M White  Correspondence email
Jacqueline S Gerritsen
1Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
2Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
3Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA
Roles: Conceptualization, Formal analysis, Validation, Investigation, Writing—original draft, Writing—review and editing
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Joseph S Faraguna
1Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
Roles: Investigation, Writing—original draft
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Rudy Bonavia
4Ludwig Institute for Cancer Research, La Jolla, CA, USA
Roles: Resources, Investigation
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Frank B Furnari
4Ludwig Institute for Cancer Research, La Jolla, CA, USA
5Moores Cancer Center, University of California at San Diego, La Jolla, CA, USA
6Department of Medicine, University of California at San Diego, La Jolla, CA, USA
Roles: Conceptualization, Resources, Supervision, Writing—original draft
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Forest M White
1Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
2Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
3Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA
Roles: Conceptualization, Formal analysis, Supervision, Funding acquisition, Writing—original draft, Project administration, Writing—review and editing
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  • ORCID record for Forest M White
  • For correspondence: fwhite@mit.edu
Published 11 May 2023. DOI: 10.26508/lsa.202201466
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Article Information

vol. 6 no. 8 e202201466
DOI 
https://doi.org/10.26508/lsa.202201466
PubMed 
37169593

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received March 28, 2022
  • Revision received April 30, 2023
  • Accepted May 1, 2023
  • Published online May 11, 2023.

Copyright & Usage 
© 2023 Gerritsen et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Jacqueline S Gerritsen1,2,3, Conceptualization, Formal analysis, Validation, Investigation, Writing—original draft, Writing—review and editing,
  2. Joseph S Faraguna1, Investigation, Writing—original draft,
  3. Rudy Bonavia4, Resources, Investigation,
  4. Frank B Furnari4,5,6, Conceptualization, Resources, Supervision, Writing—original draft and
  5. Forest M White1,2,3, Conceptualization, Formal analysis, Supervision, Funding acquisition, Writing—original draft, Project administration, Writing—review and editing⇑
  1. 1Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
  2. 2Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
  3. 3Center for Precision Cancer Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA
  4. 4Ludwig Institute for Cancer Research, La Jolla, CA, USA
  5. 5Moores Cancer Center, University of California at San Diego, La Jolla, CA, USA
  6. 6Department of Medicine, University of California at San Diego, La Jolla, CA, USA
  1. Correspondence: fwhite{at}mit.edu
View Full Text

Funding

  • HHS | NIH | National Cancer Institute (NCI)

    U54 CA210180
    FM White
  • HHS | NIH | National Cancer Institute (NCI)

    U01 CA238720
    FM White
  • National Institutes of Health

    R01 GM139998, P30 CA14051
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Data-driven modeling of EGFR C-terminal tyrosine function
Jacqueline S Gerritsen, Joseph S Faraguna, Rudy Bonavia, Frank B Furnari, Forest M White
Life Science Alliance May 2023, 6 (8) e202201466; DOI: 10.26508/lsa.202201466

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Data-driven modeling of EGFR C-terminal tyrosine function
Jacqueline S Gerritsen, Joseph S Faraguna, Rudy Bonavia, Frank B Furnari, Forest M White
Life Science Alliance May 2023, 6 (8) e202201466; DOI: 10.26508/lsa.202201466
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Volume 6, No. 8
August 2023
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