The histone H4K20 methyltransferase SUV4-20H1/KMT5B is required for multiciliated cell differentiation in Xenopus

Alessandro Angerilli; Janet Tait; Julian Berges; Irina Shcherbakova; Daniil Pokrovsky; Tamas Schauer; Pawel Smialowski; Ohnmar Hsam; Edith Mentele; Dario Nicetto; Ralph AW Rupp

doi:10.26508/lsa.202302023

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The histone H4K20 methyltransferase SUV4-20H1/KMT5B is required for multiciliated cell differentiation in Xenopus

Alessandro Angerilli, View ORCID ProfileJanet Tait, Julian Berges, Irina Shcherbakova, View ORCID ProfileDaniil Pokrovsky, View ORCID ProfileTamas Schauer, Pawel Smialowski, Ohnmar Hsam, Edith Mentele, View ORCID ProfileDario Nicetto, View ORCID ProfileRalph AW Rupp Correspondence email

Alessandro Angerilli

1Department of Molecular Biology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany

Roles: Validation, Investigation, Visualization, Methodology, Writing—original draft

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Janet Tait

1Department of Molecular Biology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany

Roles: Validation, Investigation, Visualization, Methodology, Writing—original draft, Writing—review and editing

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ORCID record for Janet Tait

Julian Berges

1Department of Molecular Biology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany

2Sektion Pädiatrische Pneumologie und Allergologie und Mukoviszidose-Zentrum, Universitäts-Klinikum Heidelberg, Heidelberg, Germany

Roles: Investigation, Methodology

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Irina Shcherbakova

1Department of Molecular Biology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany

Roles: Investigation

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Daniil Pokrovsky

1Department of Molecular Biology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany

Roles: Investigation, Visualization

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Tamas Schauer

1Department of Molecular Biology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany

Roles: Data curation, Software, Formal analysis, Visualization

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ORCID record for Tamas Schauer

Pawel Smialowski

3Institute for Stem Cell Research, Helmholtz Centre Munich, Neuherberg, Germany

4Department of Physiological Genomics, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany

Roles: Data curation, Software, Formal analysis

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Ohnmar Hsam

1Department of Molecular Biology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany

5Klinik und Poliklinik für Neurologie der Universität Regensburg, Regensburg, Germany

Roles: Investigation

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Edith Mentele

1Department of Molecular Biology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany

Roles: Investigation

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Dario Nicetto

1Department of Molecular Biology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany

6Ambys Medicines, South San Francisco, CA, USA

Roles: Investigation, Methodology

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Ralph AW Rupp

1Department of Molecular Biology, Biomedical Center, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany

Roles: Conceptualization, Resources, Supervision, Funding acquisition, Investigation, Methodology, Writing—original draft, Project administration, Writing—review and editing

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ORCID record for Ralph AW Rupp
For correspondence: ralph.rupp@bmc.med.lmu.de

Published 28 April 2023. DOI: 10.26508/lsa.202302023

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SUV4-20H1 required for motile cilia tuft formation

Alessandro Angerilli, Janet Tait, Julian Berges, Irina Shcherbakova, Daniil Pokrovsky, Tamas Schauer, Pawel Smialowski, Ohnmar Hsam, Edith Mentele, Dario Nicetto, Ralph AW Rupp

Life Science Alliance Apr 2023, 6 (7) e202302023; DOI: 10.26508/lsa.202302023

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SUV4-20H1 required for motile cilia tuft formation

Alessandro Angerilli, Janet Tait, Julian Berges, Irina Shcherbakova, Daniil Pokrovsky, Tamas Schauer, Pawel Smialowski, Ohnmar Hsam, Edith Mentele, Dario Nicetto, Ralph AW Rupp

Life Science Alliance Apr 2023, 6 (7) e202302023; DOI: 10.26508/lsa.202302023

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