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Mitochondrial dysfunction rapidly modulates the abundance and thermal stability of cellular proteins

Carina Groh, Per Haberkant, Frank Stein, Sebastian Filbeck, Stefan Pfeffer, Mikhail M Savitski, Felix Boos  Correspondence email, Johannes M Herrmann  Correspondence email
Published 20 March 2023. DOI: 10.26508/lsa.202201805

Article Information

vol. 6 no. 6 e202201805
DOI 
https://doi.org/10.26508/lsa.202201805
PubMed 
36941057
Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received November 4, 2022
  • Revision received March 3, 2023
  • Accepted March 3, 2023
  • Published online March 20, 2023.
Copyright & Usage 
© 2023 Groh et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Carina Groh1, Conceptualization, Data curation, Formal analysis, Validation, Investigation, Visualization, Methodology, Writing—review and editing,
  2. Per Haberkant2, Data curation, Formal analysis, Visualization, Methodology, Writing—review and editing,
  3. Frank Stein2, Data curation, Software, Formal analysis, Investigation, Visualization, Methodology, Writing—review and editing,
  4. Sebastian Filbeck3, Formal analysis, Investigation, Visualization, Writing—review and editing,
  5. Stefan Pfeffer3, Validation, Investigation, Visualization, Writing—review and editing,
  6. Mikhail M Savitski2, Conceptualization, Investigation, Methodology, Writing—review and editing,
  7. Felix Boos1, Conceptualization, Data curation, Formal analysis, Supervision, Investigation, Visualization, Methodology, Project administration, Writing—review and editing⇑ and
  8. Johannes M Herrmann1, Conceptualization, Data curation, Supervision, Investigation, Visualization, Writing—original draft, Project administration, Writing—review and editing⇑
  1. 1Cell Biology, University of Kaiserslautern, Kaiserslautern, Germany;
  2. 2Proteomics Core Facility, EMBL Heidelberg, Heidelberg, Germany;
  3. 3ZMBH, University Heidelberg, Heidelberg, Germany
  1. Correspondence: hannes.herrmann{at}biologie.uni-kl.de
  2. fboos{at}stanford.edu

  • Felix Boos’s present address is Department of Genetics, Stanford University, Stanford, CA, USA

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Funding

  • EC | European Research Council (ERC)

    101052639 MitoCyto
    JM Herrmann

  • Deutsche Forschungsgemeinschaft (DFG)

    HE2803/10-1; GRK2737-STRESSistance
    JM Herrmann

  • Landesforschungsinitiative Rheinland-Pfalz

    BioComp
    JM Herrmann

  • Damon Runyon Cancer Research Foundation (DRCRF)

    DRG-2461-22
    F Boos

  • Joachim Herz Stiftung (Joachim Herz Foundation)

    F Boos

  • Joachim Herz Stiftung (Joachim Herz Foundation)

    C Groh
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ppTPP reveals rapid proteome remodeling
Carina Groh, Per Haberkant, Frank Stein, Sebastian Filbeck, Stefan Pfeffer, Mikhail M Savitski, Felix Boos, Johannes M Herrmann
Life Science Alliance Mar 2023, 6 (6) e202201805; DOI: 10.26508/lsa.202201805
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Volume 6, No. 6
June 2023
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