Crystal structures of dimeric and heptameric mtHsp60 reveal the mechanism of chaperonin inactivation

Meng-Cheng Lai; Hao-Yu Cheng; Sin-Hong Lew; Yu-An Chen; Chien-Hung Yu; Han-You Lin; Shih-Ming Lin

doi:10.26508/lsa.202201753

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Crystal structures of dimeric and heptameric mtHsp60 reveal the mechanism of chaperonin inactivation

Meng-Cheng Lai, View ORCID ProfileHao-Yu Cheng, Sin-Hong Lew, Yu-An Chen, Chien-Hung Yu, Han-You Lin, View ORCID ProfileShih-Ming Lin Correspondence email

Meng-Cheng Lai

1Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, Taiwan

Roles: Data curation, Formal analysis, Writing—original draft

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Hao-Yu Cheng

1Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, Taiwan

Roles: Data curation, Formal analysis

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ORCID record for Hao-Yu Cheng

Sin-Hong Lew

1Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, Taiwan

Roles: Data curation, Formal analysis

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Yu-An Chen

1Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, Taiwan

Roles: Data curation, Software, Formal analysis

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Chien-Hung Yu

2Department of Biochemistry and Molecular Biology, National Cheng Kung University, Tainan, Taiwan

5Institute of Basic Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan

Roles: Conceptualization, Resources, Writing—review and editing

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Han-You Lin

3Department of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan

Roles: Conceptualization, Methodology, Writing—review and editing

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Shih-Ming Lin

1Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, Taiwan

4Institute of Tropical Plant Sciences and Microbiology, National Cheng Kung University, Tainan, Taiwan

Roles: Conceptualization, Supervision, Writing—original draft, Writing—review and editing

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ORCID record for Shih-Ming Lin
For correspondence: smlin@mail.ncku.edu.tw

Published 27 March 2023. DOI: 10.26508/lsa.202201753

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Dimeric mtHsp60 with Inactive ATPase Activity

Meng-Cheng Lai, Hao-Yu Cheng, Sin-Hong Lew, Yu-An Chen, Chien-Hung Yu, Han-You Lin, Shih-Ming Lin

Life Science Alliance Mar 2023, 6 (6) e202201753; DOI: 10.26508/lsa.202201753

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Dimeric mtHsp60 with Inactive ATPase Activity

Meng-Cheng Lai, Hao-Yu Cheng, Sin-Hong Lew, Yu-An Chen, Chien-Hung Yu, Han-You Lin, Shih-Ming Lin

Life Science Alliance Mar 2023, 6 (6) e202201753; DOI: 10.26508/lsa.202201753

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