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Transcriptome analyses in infertile men reveal germ cell–specific expression and splicing patterns

View ORCID ProfileLara M Siebert-Kuss, Henrike Krenz, View ORCID ProfileTobias Tekath, Marius Wöste, View ORCID ProfileSara Di Persio, Nicole Terwort, Margot J Wyrwoll, Jann-Frederik Cremers, View ORCID ProfileJoachim Wistuba, View ORCID ProfileMartin Dugas, Sabine Kliesch, Stefan Schlatt, View ORCID ProfileFrank Tüttelmann, Jörg Gromoll, View ORCID ProfileNina Neuhaus, View ORCID ProfileSandra Laurentino  Correspondence email
Lara M Siebert-Kuss
1Centre of Reproductive Medicine and Andrology, Institute of Reproductive and Regenerative Biology, University of Münster, Münster, Germany
Roles: Formal analysis, Validation, Visualization, Writing—original draft, review, and editing
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  • ORCID record for Lara M Siebert-Kuss
Henrike Krenz
2Institute of Medical Informatics, University of Münster, Münster, Germany
Roles: Data curation, Software, Formal analysis, Visualization, Methodology, Writing—original draft
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Tobias Tekath
2Institute of Medical Informatics, University of Münster, Münster, Germany
Roles: Data curation, Software, Methodology, Writing—original draft
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  • ORCID record for Tobias Tekath
Marius Wöste
2Institute of Medical Informatics, University of Münster, Münster, Germany
Roles: Data curation, Software, Methodology, Writing—original draft
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Sara Di Persio
1Centre of Reproductive Medicine and Andrology, Institute of Reproductive and Regenerative Biology, University of Münster, Münster, Germany
Roles: Formal analysis, Investigation, Writing—original draft, review, and editing
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  • ORCID record for Sara Di Persio
Nicole Terwort
1Centre of Reproductive Medicine and Andrology, Institute of Reproductive and Regenerative Biology, University of Münster, Münster, Germany
Roles: Formal analysis, Investigation, Methodology, Writing—original draft
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Margot J Wyrwoll
3Institute of Reproductive Genetics, University of Münster, Münster, Germany
Roles: Resources, Data curation, Formal analysis, Investigation, Methodology, Writing—original draft, review, and editing
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Jann-Frederik Cremers
4Department of Clinical and Surgical Andrology, Centre of Reproductive Medicine and Andrology, University Hospital of Münster, Münster, Germany
Roles: Resources, Data curation, Investigation, Writing—review and editing
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Joachim Wistuba
1Centre of Reproductive Medicine and Andrology, Institute of Reproductive and Regenerative Biology, University of Münster, Münster, Germany
Roles: Formal analysis, Investigation, Methodology, Writing—review and editing
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  • ORCID record for Joachim Wistuba
Martin Dugas
2Institute of Medical Informatics, University of Münster, Münster, Germany
5Institute of Medical Informatics, Heidelberg University Hospital, Heidelberg, Germany
Roles: Software, Methodology, Writing—review and editing
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  • ORCID record for Martin Dugas
Sabine Kliesch
4Department of Clinical and Surgical Andrology, Centre of Reproductive Medicine and Andrology, University Hospital of Münster, Münster, Germany
Roles: Data curation, Investigation, Writing—review and editing
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Stefan Schlatt
1Centre of Reproductive Medicine and Andrology, Institute of Reproductive and Regenerative Biology, University of Münster, Münster, Germany
Roles: Resources, Investigation, Writing—review and editing
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Frank Tüttelmann
3Institute of Reproductive Genetics, University of Münster, Münster, Germany
Roles: Conceptualization, Data curation, Formal analysis, Funding acquisition, Writing—original draft, review, and editing
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  • ORCID record for Frank Tüttelmann
Jörg Gromoll
1Centre of Reproductive Medicine and Andrology, Institute of Reproductive and Regenerative Biology, University of Münster, Münster, Germany
Roles: Conceptualization, Funding acquisition, Investigation, Methodology, Writing—original draft, review, and editing
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Nina Neuhaus
1Centre of Reproductive Medicine and Andrology, Institute of Reproductive and Regenerative Biology, University of Münster, Münster, Germany
Roles: Conceptualization, Formal analysis, Supervision, Funding acquisition, Methodology, Project administration, Writing—original draft, review, and editing
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  • ORCID record for Nina Neuhaus
Sandra Laurentino
1Centre of Reproductive Medicine and Andrology, Institute of Reproductive and Regenerative Biology, University of Münster, Münster, Germany
Roles: Conceptualization, Supervision, Funding acquisition, Investigation, Visualization, Methodology, Project administration, Writing—original draft, review, and editing
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  • ORCID record for Sandra Laurentino
  • For correspondence: Sandra.Laurentino@ukmuenster.de
Published 29 November 2022. DOI: 10.26508/lsa.202201633
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Transcriptome analyses in infertile men reveal germ cell–specific expression and splicing patterns
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Transcriptome of human male germ cells
Lara M Siebert-Kuss, Henrike Krenz, Tobias Tekath, Marius Wöste, Sara Di Persio, Nicole Terwort, Margot J Wyrwoll, Jann-Frederik Cremers, Joachim Wistuba, Martin Dugas, Sabine Kliesch, Stefan Schlatt, Frank Tüttelmann, Jörg Gromoll, Nina Neuhaus, Sandra Laurentino
Life Science Alliance Nov 2022, 6 (2) e202201633; DOI: 10.26508/lsa.202201633

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Transcriptome of human male germ cells
Lara M Siebert-Kuss, Henrike Krenz, Tobias Tekath, Marius Wöste, Sara Di Persio, Nicole Terwort, Margot J Wyrwoll, Jann-Frederik Cremers, Joachim Wistuba, Martin Dugas, Sabine Kliesch, Stefan Schlatt, Frank Tüttelmann, Jörg Gromoll, Nina Neuhaus, Sandra Laurentino
Life Science Alliance Nov 2022, 6 (2) e202201633; DOI: 10.26508/lsa.202201633
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Volume 6, No. 2
February 2023
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  • Genetics, Gene Therapy & Genetic Disease
  • Medical Research
  • Molecular Biology

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