Loss of cell–cell adhesion triggers cell migration through Rac1-dependent ROS generation

Yu-Hsuan Chen; Jinn-Yuan Hsu; Ching-Tung Chu; Yao-Wen Chang; Jia-Rong Fan; Muh-Hwa Yang; Hong-Chen Chen

doi:10.26508/lsa.202201529

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Loss of cell–cell adhesion triggers cell migration through Rac1-dependent ROS generation

View ORCID ProfileYu-Hsuan Chen, Jinn-Yuan Hsu, View ORCID ProfileChing-Tung Chu, Yao-Wen Chang, Jia-Rong Fan, Muh-Hwa Yang, View ORCID ProfileHong-Chen Chen Correspondence email

Yu-Hsuan Chen

1Institute of Biochemistry and Molecular Biology, School of Life Science, National Yang Ming Chiao Tung University, Taipei, Taiwan

2Cancer Progression Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan

Roles: Data curation, Formal analysis, Investigation

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ORCID record for Yu-Hsuan Chen

Jinn-Yuan Hsu

1Institute of Biochemistry and Molecular Biology, School of Life Science, National Yang Ming Chiao Tung University, Taipei, Taiwan

2Cancer Progression Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan

Roles: Data curation, Formal analysis, Investigation, Methodology

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Ching-Tung Chu

1Institute of Biochemistry and Molecular Biology, School of Life Science, National Yang Ming Chiao Tung University, Taipei, Taiwan

2Cancer Progression Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan

Roles: Validation, Visualization

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ORCID record for Ching-Tung Chu

Yao-Wen Chang

3Institute of Clinical Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan

Roles: Data curation, Formal analysis, Investigation

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Jia-Rong Fan

1Institute of Biochemistry and Molecular Biology, School of Life Science, National Yang Ming Chiao Tung University, Taipei, Taiwan

2Cancer Progression Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan

Roles: Investigation

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Muh-Hwa Yang

2Cancer Progression Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan

3Institute of Clinical Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan

4Division of Medical Oncology, Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan

Roles: Conceptualization, Data curation, Supervision

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Hong-Chen Chen

1Institute of Biochemistry and Molecular Biology, School of Life Science, National Yang Ming Chiao Tung University, Taipei, Taiwan

2Cancer Progression Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan

Roles: Conceptualization, Data curation, Formal analysis, Supervision, Funding acquisition, Writing—review and editing

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ORCID record for Hong-Chen Chen
For correspondence: hcchen1029@nycu.edu.tw

Published 29 November 2022. DOI: 10.26508/lsa.202201529

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Rac1 triggers cell migration upon loss of cell–cell adhesion

Yu-Hsuan Chen, Jinn-Yuan Hsu, Ching-Tung Chu, Yao-Wen Chang, Jia-Rong Fan, Muh-Hwa Yang, Hong-Chen Chen

Life Science Alliance Nov 2022, 6 (2) e202201529; DOI: 10.26508/lsa.202201529

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Rac1 triggers cell migration upon loss of cell–cell adhesion

Yu-Hsuan Chen, Jinn-Yuan Hsu, Ching-Tung Chu, Yao-Wen Chang, Jia-Rong Fan, Muh-Hwa Yang, Hong-Chen Chen

Life Science Alliance Nov 2022, 6 (2) e202201529; DOI: 10.26508/lsa.202201529

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February 2023

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