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Research Article
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Nanoscaled RIM clustering at presynaptic active zones revealed by endogenous tagging

View ORCID ProfileAchmed Mrestani, View ORCID ProfileSven Dannhäuser, Martin Pauli, Philip Kollmannsberger, View ORCID ProfileMartha Hübsch, Lydia Morris, View ORCID ProfileTobias Langenhan, View ORCID ProfileManfred Heckmann  Correspondence email, View ORCID ProfileMila M Paul  Correspondence email
Achmed Mrestani
1Department of Neurophysiology, Institute of Physiology, University of Würzburg, Würzburg, Germany
2Department of Neurology, Leipzig University Medical Center, Leipzig, Germany
3Division of General Biochemistry, Rudolf Schönheimer Institute of Biochemistry, Medical Faculty, Leipzig University, Leipzig, Germany
Roles: Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Visualization, Writing—original draft
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  • ORCID record for Achmed Mrestani
Sven Dannhäuser
1Department of Neurophysiology, Institute of Physiology, University of Würzburg, Würzburg, Germany
Roles: Data curation, Formal analysis, Investigation, Writing—review and editing
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  • ORCID record for Sven Dannhäuser
Martin Pauli
1Department of Neurophysiology, Institute of Physiology, University of Würzburg, Würzburg, Germany
Roles: Software, Formal analysis, Validation, Investigation
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Philip Kollmannsberger
4Biomedical Physics, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
Roles: Software, Formal analysis, Writing—review and editing
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Martha Hübsch
1Department of Neurophysiology, Institute of Physiology, University of Würzburg, Würzburg, Germany
Roles: Investigation
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  • ORCID record for Martha Hübsch
Lydia Morris
3Division of General Biochemistry, Rudolf Schönheimer Institute of Biochemistry, Medical Faculty, Leipzig University, Leipzig, Germany
Roles: Investigation
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Tobias Langenhan
3Division of General Biochemistry, Rudolf Schönheimer Institute of Biochemistry, Medical Faculty, Leipzig University, Leipzig, Germany
Roles: Conceptualization, Funding acquisition, Writing—review and editing
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  • ORCID record for Tobias Langenhan
Manfred Heckmann
1Department of Neurophysiology, Institute of Physiology, University of Würzburg, Würzburg, Germany
Roles: Conceptualization, Resources, Supervision, Funding acquisition, Validation, Methodology, Writing—original draft, Project administration
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  • For correspondence: heckmann@uni-wuerzburg.de
Mila M Paul
1Department of Neurophysiology, Institute of Physiology, University of Würzburg, Würzburg, Germany
5Department of Orthopedic Trauma, Hand, Plastic and Reconstructive Surgery, University Hospital of Würzburg, Würzburg, Germany
Roles: Conceptualization, Data curation, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Visualization, Writing—original draft, Project administration
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  • For correspondence: mila.paul@uni-wuerzburg.de
Published 11 September 2023. DOI: 10.26508/lsa.202302021
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Article Information

vol. 6 no. 12 e202302021
DOI 
https://doi.org/10.26508/lsa.202302021
PubMed 
37696575

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received March 2, 2023
  • Revision received August 27, 2023
  • Accepted August 28, 2023
  • Published online September 11, 2023.

Copyright & Usage 
© 2023 Mrestani et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Achmed Mrestani1,2,3,*, Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Visualization, Writing—original draft,
  2. Sven Dannhäuser1,*, Data curation, Formal analysis, Investigation, Writing—review and editing,
  3. Martin Pauli1, Software, Formal analysis, Validation, Investigation,
  4. Philip Kollmannsberger4, Software, Formal analysis, Writing—review and editing,
  5. Martha Hübsch1, Investigation,
  6. Lydia Morris3, Investigation,
  7. Tobias Langenhan3, Conceptualization, Funding acquisition, Writing—review and editing,
  8. Manfred Heckmann1, Conceptualization, Resources, Supervision, Funding acquisition, Validation, Methodology, Writing—original draft, Project administration⇑ and
  9. Mila M Paul1,5, Conceptualization, Data curation, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Visualization, Writing—original draft, Project administration⇑
  1. 1Department of Neurophysiology, Institute of Physiology, University of Würzburg, Würzburg, Germany
  2. 2Department of Neurology, Leipzig University Medical Center, Leipzig, Germany
  3. 3Division of General Biochemistry, Rudolf Schönheimer Institute of Biochemistry, Medical Faculty, Leipzig University, Leipzig, Germany
  4. 4Biomedical Physics, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
  5. 5Department of Orthopedic Trauma, Hand, Plastic and Reconstructive Surgery, University Hospital of Würzburg, Würzburg, Germany
  1. Correspondence: heckmann{at}uni-wuerzburg.de
  2. mila.paul{at}uni-wuerzburg.de
  1. ↵* Achmed Mrestani and Sven Dannhäuser contributed equally to this work

View Full Text

Funding

  • Deutsche Forschungsgemeinschaft (DFG)

    3004 SYNABS P1
    M Heckmann
  • Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Würzburg (IZKF Würzburg)

    N229
    M Heckmann
  • Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Würzburg (IZKF Würzburg)

    Z-3/69
    Mila M Paul
  • Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Würzburg (IZKF Würzburg)

    HB22PAUL
    Mila M Paul
  • Deutsche Forschungsgemeinschaft (DFG)

    CRC 1423 project number 421152132
    T Langenhan
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RIM nanoclusters at presynaptic active zones
Achmed Mrestani, Sven Dannhäuser, Martin Pauli, Philip Kollmannsberger, Martha Hübsch, Lydia Morris, Tobias Langenhan, Manfred Heckmann, Mila M Paul
Life Science Alliance Sep 2023, 6 (12) e202302021; DOI: 10.26508/lsa.202302021

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RIM nanoclusters at presynaptic active zones
Achmed Mrestani, Sven Dannhäuser, Martin Pauli, Philip Kollmannsberger, Martha Hübsch, Lydia Morris, Tobias Langenhan, Manfred Heckmann, Mila M Paul
Life Science Alliance Sep 2023, 6 (12) e202302021; DOI: 10.26508/lsa.202302021
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Volume 6, No. 12
December 2023
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