PASCAR: a multiscale framework to explore the design space of constitutive and inducible CAR T cells

Harshana Rajakaruna; Milie Desai; Jayajit Das

doi:10.26508/lsa.202302171

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PASCAR: a multiscale framework to explore the design space of constitutive and inducible CAR T cells

Harshana Rajakaruna, Milie Desai, View ORCID ProfileJayajit Das Correspondence email

Harshana Rajakaruna

1The Steve and Cindy Rasmussen Institute for Genomics, The Abigail Wexner Research Institute, Nationwide Children’s Hospital, Columbus, OH, USA

Roles: Data curation, Software, Formal analysis, Investigation, Visualization, Methodology, Writing—original draft, Writing—review and editing

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Milie Desai

2Department of Biology, Indian Institute of Science Education and Research, Pune, India

Roles: Data curation, Software, Investigation, Methodology, Writing—original draft

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Jayajit Das

1The Steve and Cindy Rasmussen Institute for Genomics, The Abigail Wexner Research Institute, Nationwide Children’s Hospital, Columbus, OH, USA

3Department of Pediatrics and Pelotonia Institute for Immuno-Oncology, College of Medicine, Columbus, OH, USA

4Biophysics Program, The Ohio State University, Columbus, OH, USA

Roles: Conceptualization, Resources, Formal analysis, Supervision, Funding acquisition, Investigation, Methodology, Writing—original draft, Project administration, Writing—review and editing

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ORCID record for Jayajit Das
For correspondence: jayajit{at}gmail.com

Published 28 July 2023. DOI: 10.26508/lsa.202302171

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A multiscale framework to explore CAR T cell design space

Harshana Rajakaruna, Milie Desai, Jayajit Das

Life Science Alliance Jul 2023, 6 (10) e202302171; DOI: 10.26508/lsa.202302171

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A multiscale framework to explore CAR T cell design space

Harshana Rajakaruna, Milie Desai, Jayajit Das

Life Science Alliance Jul 2023, 6 (10) e202302171; DOI: 10.26508/lsa.202302171

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