CRISPRi screening reveals regulators of tau pathology shared between exosomal and vesicle-free tau

Juan Carlos Polanco; Yevhen Akimov; Avinash Fernandes; Adam Briner; Gabriel Rhys Hand; Marloes van Roijen; Giuseppe Balistreri; Jürgen Götz

doi:10.26508/lsa.202201689

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CRISPRi screening reveals regulators of tau pathology shared between exosomal and vesicle-free tau

View ORCID ProfileJuan Carlos Polanco Correspondence email, Yevhen Akimov, Avinash Fernandes, Adam Briner, Gabriel Rhys Hand, Marloes van Roijen, View ORCID ProfileGiuseppe Balistreri, View ORCID ProfileJürgen Götz Correspondence email

Juan Carlos Polanco

1Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Australia

Roles: Conceptualization, Resources, Data curation, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Visualization, Methodology, Writing—original draft, review, and editing

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ORCID record for Juan Carlos Polanco
For correspondence: j.polanco{at}uq.edu.au j.goetz{at}uq.edu.au

Yevhen Akimov

2Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland

Roles: Resources, Data curation, Software, Formal analysis, Investigation, Methodology, Writing—original draft

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Avinash Fernandes

1Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Australia

Roles: Data curation, Formal analysis, Validation, Investigation, Visualization, Methodology, Writing—original draft

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Adam Briner

1Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Australia

Roles: Data curation, Formal analysis, Investigation, Methodology, Writing—original draft

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Gabriel Rhys Hand

1Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Australia

Roles: Data curation, Formal analysis, Investigation, Methodology, Writing—original draft

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Marloes van Roijen

4New South Wales Brain Bank, The University of Sydney, Sydney, Australia

Roles: Resources, Data curation, Formal analysis, Investigation

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Giuseppe Balistreri

3Faculty of Biological and Environmental Sciences, Molecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki, Finland

Roles: Conceptualization, Data curation, Formal analysis, Funding acquisition, Validation, Investigation, Visualization, Methodology, Writing—original draft

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ORCID record for Giuseppe Balistreri

Jürgen Götz

1Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Australia

Roles: Resources, Formal analysis, Supervision, Funding acquisition, Visualization, Writing—original draft, review, and editing

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ORCID record for Jürgen Götz
For correspondence: j.polanco{at}uq.edu.au j.goetz{at}uq.edu.au

Published 31 October 2022. DOI: 10.26508/lsa.202201689

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Novel regulators of tau pathology

Juan Carlos Polanco, Yevhen Akimov, Avinash Fernandes, Adam Briner, Gabriel Rhys Hand, Marloes van Roijen, Giuseppe Balistreri, Jürgen Götz

Life Science Alliance Oct 2022, 6 (1) e202201689; DOI: 10.26508/lsa.202201689

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Novel regulators of tau pathology

Juan Carlos Polanco, Yevhen Akimov, Avinash Fernandes, Adam Briner, Gabriel Rhys Hand, Marloes van Roijen, Giuseppe Balistreri, Jürgen Götz

Life Science Alliance Oct 2022, 6 (1) e202201689; DOI: 10.26508/lsa.202201689

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