Hepatic DKK1-driven steatosis is CD36 dependent

Zhen Yang; Xinping Huang; Jiaye Zhang; Kai You; Yue Xiong; Ji Fang; Anteneh Getachew; Ziqi Cheng; Xiaorui Yu; Yan Wang; Feima Wu; Ning Wang; Shufen Feng; Xianhua Lin; Fan Yang; Yan Chen; Hongcheng Wei; Yin-xiong Li

doi:10.26508/lsa.202201665

Research Article

Open Access

Hepatic DKK1-driven steatosis is CD36 dependent

View ORCID ProfileZhen Yang, View ORCID ProfileXinping Huang, Jiaye Zhang, Kai You, Yue Xiong, Ji Fang, Anteneh Getachew, Ziqi Cheng, Xiaorui Yu, Yan Wang, Feima Wu, Ning Wang, Shufen Feng, Xianhua Lin, Fan Yang, Yan Chen, Hongcheng Wei, View ORCID ProfileYin-xiong Li Correspondence email

Zhen Yang

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

2University of Chinese Academy of Sciences, Beijing, China

Roles: Conceptualization, Data curation, Software, Formal analysis, Validation, Investigation, Writing—original draft, Writing—review and editing

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ORCID record for Zhen Yang

Xinping Huang

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

2University of Chinese Academy of Sciences, Beijing, China

Roles: Data curation, Validation, Methodology

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ORCID record for Xinping Huang

Jiaye Zhang

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

Roles: Software, Writing—original draft

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Kai You

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

Roles: Validation, Investigation, Methodology

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Yue Xiong

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

Roles: Resources, Software, Methodology

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Ji Fang

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

Roles: Resources, Data curation

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Anteneh Getachew

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

Roles: Software, Formal analysis

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Ziqi Cheng

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

2University of Chinese Academy of Sciences, Beijing, China

Roles: Investigation, Methodology

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Xiaorui Yu

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

3School of Life Sciences, University of Science and Technology of China, Hefei, China

Roles: Investigation, Methodology

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Yan Wang

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

Roles: Investigation, Methodology

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Feima Wu

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

Roles: Formal analysis, Investigation, Methodology

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Ning Wang

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

Roles: Investigation, Methodology

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Shufen Feng

7Department of Gastroenterology, First Affiliated Hospital of Jinan University, Guangzhou, China

Roles: Resources, Data curation

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Xianhua Lin

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

Roles: Software, Funding acquisition

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Fan Yang

10Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, China

Roles: Software, Funding acquisition

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Yan Chen

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

Roles: Data curation, Investigation, Methodology

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Hongcheng Wei

7Department of Gastroenterology, First Affiliated Hospital of Jinan University, Guangzhou, China

Roles: Resources, Funding acquisition

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Yin-xiong Li

1Center for Health Research, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

2University of Chinese Academy of Sciences, Beijing, China

4Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

5CAS Key Laboratory of Regenerative Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

6Guangdong Provincial Key Laboratory of Biocomputing, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

8State Key Laboratory of Respiratory Disease, Guangzhou, China

9China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou, China

Roles: Supervision, Funding acquisition, Validation, Visualization, Project administration, Writing—review and editing

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ORCID record for Yin-xiong Li
For correspondence: li_yinxiong@gibh.ac.cn

Published 21 November 2022. DOI: 10.26508/lsa.202201665

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DKK1-driven hepatic steatosis

Zhen Yang, Xinping Huang, Jiaye Zhang, Kai You, Yue Xiong, Ji Fang, Anteneh Getachew, Ziqi Cheng, Xiaorui Yu, Yan Wang, Feima Wu, Ning Wang, Shufen Feng, Xianhua Lin, Fan Yang, Yan Chen, Hongcheng Wei, Yin-xiong Li

Life Science Alliance Nov 2022, 6 (1) e202201665; DOI: 10.26508/lsa.202201665

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DKK1-driven hepatic steatosis

Life Science Alliance Nov 2022, 6 (1) e202201665; DOI: 10.26508/lsa.202201665

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