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Research Article
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miR-486 is essential for muscle function and suppresses a dystrophic transcriptome

Adrienne Samani, Rylie M Hightower, Andrea L Reid, View ORCID ProfileKatherine G English, View ORCID ProfileMichael A Lopez, J Scott Doyle, Michael J Conklin, View ORCID ProfileDavid A Schneider, Marcas M Bamman, View ORCID ProfileJeffrey J Widrick, View ORCID ProfileDavid K Crossman, Min Xie, David Jee, View ORCID ProfileEric C Lai, View ORCID ProfileMatthew S Alexander  Correspondence email
Adrienne Samani
1Department of Pediatrics, Division of Neurology at Children’s of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA
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Rylie M Hightower
1Department of Pediatrics, Division of Neurology at Children’s of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA
2University of Alabama at Birmingham Center for Exercise Medicine (UCEM), Birmingham, AL, USA
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Andrea L Reid
1Department of Pediatrics, Division of Neurology at Children’s of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA
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Katherine G English
1Department of Pediatrics, Division of Neurology at Children’s of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA
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  • ORCID record for Katherine G English
Michael A Lopez
1Department of Pediatrics, Division of Neurology at Children’s of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA
2University of Alabama at Birmingham Center for Exercise Medicine (UCEM), Birmingham, AL, USA
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  • ORCID record for Michael A Lopez
J Scott Doyle
3Department of Orthopedic Surgery, at the University of Alabama at Birmingham, Birmingham, AL, USA
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Michael J Conklin
3Department of Orthopedic Surgery, at the University of Alabama at Birmingham, Birmingham, AL, USA
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David A Schneider
4Department of Biochemistry and Molecular Genetics at the University of Alabama at Birmingham, Birmingham, AL, USA
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  • ORCID record for David A Schneider
Marcas M Bamman
2University of Alabama at Birmingham Center for Exercise Medicine (UCEM), Birmingham, AL, USA
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Jeffrey J Widrick
5Division of Genetics and Genomics at Boston Children’s Hospital, Boston, MA, USA
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  • ORCID record for Jeffrey J Widrick
David K Crossman
6Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA
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Min Xie
7Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, School of Medicine, Birmingham, AL, USA
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David Jee
8Developmental Biology Program, Sloan Kettering Institute, New York, NY, USA
9Weill Graduate School of Medical Sciences, Cornell University, New York, NY, USA
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Eric C Lai
8Developmental Biology Program, Sloan Kettering Institute, New York, NY, USA
9Weill Graduate School of Medical Sciences, Cornell University, New York, NY, USA
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Matthew S Alexander
1Department of Pediatrics, Division of Neurology at Children’s of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA
2University of Alabama at Birmingham Center for Exercise Medicine (UCEM), Birmingham, AL, USA
6Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA
10UAB Civitan International Research Center (CIRC), at the University of Alabama at Birmingham, Birmingham, AL, USA
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  • ORCID record for Matthew S Alexander
  • For correspondence: matthewalexander@uabmc.edu
Published 5 May 2022. DOI: 10.26508/lsa.202101215
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miR-486 regulates normal and dystrophic muscle function
Adrienne Samani, Rylie M Hightower, Andrea L Reid, Katherine G English, Michael A Lopez, J Scott Doyle, Michael J Conklin, David A Schneider, Marcas M Bamman, Jeffrey J Widrick, David K Crossman, Min Xie, David Jee, Eric C Lai, Matthew S Alexander
Life Science Alliance May 2022, 5 (9) e202101215; DOI: 10.26508/lsa.202101215

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miR-486 regulates normal and dystrophic muscle function
Adrienne Samani, Rylie M Hightower, Andrea L Reid, Katherine G English, Michael A Lopez, J Scott Doyle, Michael J Conklin, David A Schneider, Marcas M Bamman, Jeffrey J Widrick, David K Crossman, Min Xie, David Jee, Eric C Lai, Matthew S Alexander
Life Science Alliance May 2022, 5 (9) e202101215; DOI: 10.26508/lsa.202101215
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Volume 5, No. 9
September 2022
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  • Chromatin & Epigenetics
  • Genetics, Gene Therapy & Genetic Disease
  • Genomics & Functional Genomics

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