Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Newest Articles
    • Current Issue
    • Methods & Resources
    • Archive
    • Subjects
  • Collections
  • Submit
    • Submit a Manuscript
    • Author Guidelines
    • License, Copyright, Fee
    • FAQ
    • Why submit
  • About
    • About Us
    • Editors & Staff
    • Board Members
    • Licensing and Reuse
    • Reviewer Guidelines
    • Privacy Policy
    • Advertise
    • Contact Us
    • LSA LLC
  • Alerts
  • Other Publications
    • EMBO Press
    • The EMBO Journal
    • EMBO reports
    • EMBO Molecular Medicine
    • Molecular Systems Biology
    • Rockefeller University Press
    • Journal of Cell Biology
    • Journal of Experimental Medicine
    • Journal of General Physiology
    • Cold Spring Harbor Laboratory Press
    • Genes & Development
    • Genome Research

User menu

  • My alerts

Search

  • Advanced search
Life Science Alliance
  • Other Publications
    • EMBO Press
    • The EMBO Journal
    • EMBO reports
    • EMBO Molecular Medicine
    • Molecular Systems Biology
    • Rockefeller University Press
    • Journal of Cell Biology
    • Journal of Experimental Medicine
    • Journal of General Physiology
    • Cold Spring Harbor Laboratory Press
    • Genes & Development
    • Genome Research
  • My alerts
Life Science Alliance

Advanced Search

  • Home
  • Articles
    • Newest Articles
    • Current Issue
    • Methods & Resources
    • Archive
    • Subjects
  • Collections
  • Submit
    • Submit a Manuscript
    • Author Guidelines
    • License, Copyright, Fee
    • FAQ
    • Why submit
  • About
    • About Us
    • Editors & Staff
    • Board Members
    • Licensing and Reuse
    • Reviewer Guidelines
    • Privacy Policy
    • Advertise
    • Contact Us
    • LSA LLC
  • Alerts
  • Follow lsa Template on Twitter
Research Article
Transparent Process
Open Access

miR-486 is essential for muscle function and suppresses a dystrophic transcriptome

Adrienne Samani, Rylie M Hightower, Andrea L Reid, View ORCID ProfileKatherine G English, View ORCID ProfileMichael A Lopez, J Scott Doyle, Michael J Conklin, View ORCID ProfileDavid A Schneider, Marcas M Bamman, View ORCID ProfileJeffrey J Widrick, View ORCID ProfileDavid K Crossman, Min Xie, David Jee, View ORCID ProfileEric C Lai, View ORCID ProfileMatthew S Alexander  Correspondence email
Adrienne Samani
1Department of Pediatrics, Division of Neurology at Children’s of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Rylie M Hightower
1Department of Pediatrics, Division of Neurology at Children’s of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA
2University of Alabama at Birmingham Center for Exercise Medicine (UCEM), Birmingham, AL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Andrea L Reid
1Department of Pediatrics, Division of Neurology at Children’s of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Katherine G English
1Department of Pediatrics, Division of Neurology at Children’s of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Katherine G English
Michael A Lopez
1Department of Pediatrics, Division of Neurology at Children’s of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA
2University of Alabama at Birmingham Center for Exercise Medicine (UCEM), Birmingham, AL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Michael A Lopez
J Scott Doyle
3Department of Orthopedic Surgery, at the University of Alabama at Birmingham, Birmingham, AL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael J Conklin
3Department of Orthopedic Surgery, at the University of Alabama at Birmingham, Birmingham, AL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David A Schneider
4Department of Biochemistry and Molecular Genetics at the University of Alabama at Birmingham, Birmingham, AL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for David A Schneider
Marcas M Bamman
2University of Alabama at Birmingham Center for Exercise Medicine (UCEM), Birmingham, AL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jeffrey J Widrick
5Division of Genetics and Genomics at Boston Children’s Hospital, Boston, MA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Jeffrey J Widrick
David K Crossman
6Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for David K Crossman
Min Xie
7Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, School of Medicine, Birmingham, AL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David Jee
8Developmental Biology Program, Sloan Kettering Institute, New York, NY, USA
9Weill Graduate School of Medical Sciences, Cornell University, New York, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Eric C Lai
8Developmental Biology Program, Sloan Kettering Institute, New York, NY, USA
9Weill Graduate School of Medical Sciences, Cornell University, New York, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Eric C Lai
Matthew S Alexander
1Department of Pediatrics, Division of Neurology at Children’s of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA
2University of Alabama at Birmingham Center for Exercise Medicine (UCEM), Birmingham, AL, USA
6Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA
10UAB Civitan International Research Center (CIRC), at the University of Alabama at Birmingham, Birmingham, AL, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Matthew S Alexander
  • For correspondence: matthewalexander@uabmc.edu
Published 5 May 2022. DOI: 10.26508/lsa.202101215
  • Article
  • Figures & Data
  • Info
  • Metrics
  • Reviewer Comments
  • PDF
Loading

Article Information

vol. 5 no. 9 e202101215
DOI 
https://doi.org/10.26508/lsa.202101215
PubMed 
35512829

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received August 25, 2021
  • Revision received April 19, 2022
  • Accepted April 20, 2022
  • Published online May 5, 2022.

Copyright & Usage 
© 2022 Samani et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Adrienne Samani1,†,
  2. Rylie M Hightower1,2,†,
  3. Andrea L Reid1,
  4. Katherine G English1,
  5. Michael A Lopez1,2,
  6. J Scott Doyle3,
  7. Michael J Conklin3,
  8. David A Schneider4,
  9. Marcas M Bamman2,
  10. Jeffrey J Widrick5,
  11. David K Crossman6,
  12. Min Xie7,
  13. David Jee8,9,
  14. Eric C Lai8,9 and
  15. Matthew S Alexander1,2,6,10⇑
  1. 1Department of Pediatrics, Division of Neurology at Children’s of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA
  2. 2University of Alabama at Birmingham Center for Exercise Medicine (UCEM), Birmingham, AL, USA
  3. 3Department of Orthopedic Surgery, at the University of Alabama at Birmingham, Birmingham, AL, USA
  4. 4Department of Biochemistry and Molecular Genetics at the University of Alabama at Birmingham, Birmingham, AL, USA
  5. 5Division of Genetics and Genomics at Boston Children’s Hospital, Boston, MA, USA
  6. 6Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA
  7. 7Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, School of Medicine, Birmingham, AL, USA
  8. 8Developmental Biology Program, Sloan Kettering Institute, New York, NY, USA
  9. 9Weill Graduate School of Medical Sciences, Cornell University, New York, NY, USA
  10. 10UAB Civitan International Research Center (CIRC), at the University of Alabama at Birmingham, Birmingham, AL, USA
  1. Correspondence: matthewalexander{at}uabmc.edu
View Full Text

Funding

  • NIH National Institute of Neurological Disorders and Stroke

    F99NS118718
    RM Hightower
  • NIH NINDS

    NS120812
    MA Lopez
  • Kaul Pediatric Research Institute

    MA Lopez
  • NIH Nutrition and Obesity Research Center

    P30DK056336
  • Mouse Cardiovascular Core Vevo 3100 Mouse Ultrasound Facility

  • Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, HHS of the National Institutes of Health

    R01HD095897
    MS Alexander
  • Muscular Dystrophy Association

    MDA418254
    MS Alexander
  • NIH NIAMS

    U01AR071133
    MM Bamman
  • NICHD

    P2HD086851
    MM Bamman
  • NIH NHLBI

    R01HL153501; R03HL141620
    M Xie
  • NIH

    R01GM083300; R01HL135564
    EC Lai
  • MSK Core Grant

    P30CA008748
    EC Lai
PreviousNext
Back to top
Download PDF
Email Article

Thank you for your interest in spreading the word on Life Science Alliance.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
miR-486 is essential for muscle function and suppresses a dystrophic transcriptome
(Your Name) has sent you a message from Life Science Alliance
(Your Name) thought you would like to see the Life Science Alliance web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
miR-486 regulates normal and dystrophic muscle function
Adrienne Samani, Rylie M Hightower, Andrea L Reid, Katherine G English, Michael A Lopez, J Scott Doyle, Michael J Conklin, David A Schneider, Marcas M Bamman, Jeffrey J Widrick, David K Crossman, Min Xie, David Jee, Eric C Lai, Matthew S Alexander
Life Science Alliance May 2022, 5 (9) e202101215; DOI: 10.26508/lsa.202101215

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
miR-486 regulates normal and dystrophic muscle function
Adrienne Samani, Rylie M Hightower, Andrea L Reid, Katherine G English, Michael A Lopez, J Scott Doyle, Michael J Conklin, David A Schneider, Marcas M Bamman, Jeffrey J Widrick, David K Crossman, Min Xie, David Jee, Eric C Lai, Matthew S Alexander
Life Science Alliance May 2022, 5 (9) e202101215; DOI: 10.26508/lsa.202101215
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
Issue Cover

In this Issue

Volume 5, No. 9
September 2022
  • Table of Contents
  • Cover (PDF)
  • About the Cover
  • Masthead (PDF)
Advertisement

Jump to section

  • Article
    • Graphical Abstract
    • Abstract
    • Introduction
    • Results
    • Discussion
    • Materials and Methods
    • Acknowledgements
    • Footnotes
    • References
  • Figures & Data
  • Info
  • Metrics
  • Reviewer Comments
  • PDF

Subjects

  • Chromatin & Epigenetics
  • Genetics, Gene Therapy & Genetic Disease
  • Genomics & Functional Genomics

Related Articles

  • No related articles found.

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • miR-33b inhibition improves NAFLD/NASH
  • Regulation of survival of C. elegans by amphid neurons
  • Genome-wide modeling of fly metabolism
Show more Research Article

Similar Articles

EMBO Press LogoRockefeller University Press LogoCold Spring Harbor Logo

Content

  • Home
  • Newest Articles
  • Current Issue
  • Archive
  • Subject Collections

For Authors

  • Submit a Manuscript
  • Author Guidelines
  • License, copyright, Fee

Other Services

  • Alerts
  • Twitter
  • RSS Feeds

More Information

  • Editors & Staff
  • Reviewer Guidelines
  • Feedback
  • Licensing and Reuse
  • Privacy Policy

ISSN: 2575-1077
© 2023 Life Science Alliance LLC

Life Science Alliance is registered as a trademark in the U.S. Patent and Trade Mark Office and in the European Union Intellectual Property Office.