Subgenomic RNA profiling suggests novel mechanism in coronavirus gene regulation and host adaption

Lin Lyu; Ru Feng; Mingnan Zhang; Xiaoqing Xie; Yinjing Liao; Yanjiao Zhou; Xiaokui Guo; Bing Su; Yair Dorsett; Lei Chen

doi:10.26508/lsa.202101347

Research Article

Open Access

Subgenomic RNA profiling suggests novel mechanism in coronavirus gene regulation and host adaption

Lin Lyu, Ru Feng, Mingnan Zhang, Xiaoqing Xie, Yinjing Liao, Yanjiao Zhou, Xiaokui Guo, Bing Su, View ORCID ProfileYair Dorsett Correspondence email, View ORCID ProfileLei Chen Correspondence email

Lin Lyu

1Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Roles: Formal analysis, Investigation, Visualization, Methodology, Writing—original draft, review, and editing

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Ru Feng

1Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Roles: Resources, Investigation, Writing—review and editing

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Mingnan Zhang

1Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Roles: Investigation

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Xiaoqing Xie

1Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Roles: Visualization

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Yinjing Liao

2College of Chemistry, Sichuan University, Chengdu, China

Roles: Investigation

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Yanjiao Zhou

3Department of Medicine, University of Connecticut Health, Farmington, CT, USA

Roles: Supervision

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Xiaokui Guo

1Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Roles: Supervision

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Bing Su

1Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Roles: Supervision

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Yair Dorsett

3Department of Medicine, University of Connecticut Health, Farmington, CT, USA

Roles: Investigation, Visualization, Writing—original draft, Review, and editing

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ORCID record for Yair Dorsett
For correspondence: lei.chen@sjtu.edu.cn dorsett@uchc.edu

Lei Chen

1Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Roles: Supervision, Methodology, Writing—original draft, review, and editing

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ORCID record for Lei Chen
For correspondence: lei.chen@sjtu.edu.cn dorsett@uchc.edu

Published 25 April 2022. DOI: 10.26508/lsa.202101347

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sgRNA analysis of coronaviruses

Lin Lyu, Ru Feng, Mingnan Zhang, Xiaoqing Xie, Yinjing Liao, Yanjiao Zhou, Xiaokui Guo, Bing Su, Yair Dorsett, Lei Chen

Life Science Alliance Apr 2022, 5 (8) e202101347; DOI: 10.26508/lsa.202101347

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sgRNA analysis of coronaviruses

Lin Lyu, Ru Feng, Mingnan Zhang, Xiaoqing Xie, Yinjing Liao, Yanjiao Zhou, Xiaokui Guo, Bing Su, Yair Dorsett, Lei Chen

Life Science Alliance Apr 2022, 5 (8) e202101347; DOI: 10.26508/lsa.202101347

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August 2022

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