Single-cell RNA-seq reveals heterogeneity in hiPSC-derived muscle progenitors and E2F family as a key regulator of proliferation

Minas Nalbandian; Mingming Zhao; Hiroki Kato; Tatsuya Jonouchi; May Nakajima-Koyama; Takuya Yamamoto; Hidetoshi Sakurai

doi:10.26508/lsa.202101312

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Open Access

Single-cell RNA-seq reveals heterogeneity in hiPSC-derived muscle progenitors and E2F family as a key regulator of proliferation

View ORCID ProfileMinas Nalbandian, Mingming Zhao, Hiroki Kato, Tatsuya Jonouchi, May Nakajima-Koyama, View ORCID ProfileTakuya Yamamoto, View ORCID ProfileHidetoshi Sakurai Correspondence email

Minas Nalbandian

1Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan

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ORCID record for Minas Nalbandian

Mingming Zhao

1Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan

Roles: Investigation, Methodology, Writing—review and editing

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Hiroki Kato

1Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan

2Asahi Kasei Co., Ltd., Tokyo, Japan

Roles: Conceptualization, Investigation, Methodology

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Tatsuya Jonouchi

1Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan

Roles: Investigation, Methodology

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May Nakajima-Koyama

3Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan

Roles: Investigation, Methodology

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Takuya Yamamoto

3Department of Life Science Frontiers, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan

4Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan

5Medical-risk Avoidance Based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP), Kyoto, Japan

Roles: Resources, Data curation, Formal analysis, Investigation, Visualization, Methodology, Writing—review and editing

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ORCID record for Takuya Yamamoto

Hidetoshi Sakurai

1Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan

Roles: Conceptualization, Resources, Supervision, Funding acquisition, Project administration, Writing—review and editing

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ORCID record for Hidetoshi Sakurai
For correspondence: hsakurai@cira.kyoto-u.ac.jp

Published 22 April 2022. DOI: 10.26508/lsa.202101312

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Heterogeneity in hiPSC-derived muscle progenitor cells

Minas Nalbandian, Mingming Zhao, Hiroki Kato, Tatsuya Jonouchi, May Nakajima-Koyama, Takuya Yamamoto, Hidetoshi Sakurai

Life Science Alliance Apr 2022, 5 (8) e202101312; DOI: 10.26508/lsa.202101312

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Heterogeneity in hiPSC-derived muscle progenitor cells

Minas Nalbandian, Mingming Zhao, Hiroki Kato, Tatsuya Jonouchi, May Nakajima-Koyama, Takuya Yamamoto, Hidetoshi Sakurai

Life Science Alliance Apr 2022, 5 (8) e202101312; DOI: 10.26508/lsa.202101312

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