ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway

Marta Wróbel; Jarosław Cendrowski; Ewelina Szymańska; Malwina Grębowicz-Maciukiewicz; Noga Budick-Harmelin; Matylda Macias; Aleksandra Szybińska; Michał Mazur; Krzysztof Kolmus; Krzysztof Goryca; Michalina Dąbrowska; Agnieszka Paziewska; Michał Mikula; Marta Miączyńska

doi:10.26508/lsa.202101239

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ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway

View ORCID ProfileMarta Wróbel, View ORCID ProfileJarosław Cendrowski Correspondence email, View ORCID ProfileEwelina Szymańska, View ORCID ProfileMalwina Grębowicz-Maciukiewicz, Noga Budick-Harmelin, Matylda Macias, Aleksandra Szybińska, Michał Mazur, View ORCID ProfileKrzysztof Kolmus, Krzysztof Goryca, Michalina Dąbrowska, Agnieszka Paziewska, Michał Mikula, View ORCID ProfileMarta Miączyńska Correspondence email

Marta Wróbel

1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland

Roles: Conceptualization, Data curation, Formal analysis, Validation, Investigation, Visualization, Methodology, Writing—original draft, This author and J Cendrowski contributed equally

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ORCID record for Marta Wróbel

Jarosław Cendrowski

1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland

Roles: Conceptualization, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Visualization, Project administration, Writing—original draft, review, and editing, This author and M Wrobel contributed equally

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ORCID record for Jarosław Cendrowski
For correspondence: miaczynska@iimcb.gov.pl jcendrowski@iimcb.gov.pl

Ewelina Szymańska

1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland

Roles: Validation, Investigation, Visualization

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ORCID record for Ewelina Szymańska

Malwina Grębowicz-Maciukiewicz

1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland

Roles: Investigation, Visualization

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ORCID record for Malwina Grębowicz-Maciukiewicz

Noga Budick-Harmelin

1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland

Roles: Investigation

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Matylda Macias

2Microscopy and Cytometry Facility, International Institute of Molecular and Cell Biology, Warsaw, Poland

Roles: Visualization, Methodology

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Aleksandra Szybińska

2Microscopy and Cytometry Facility, International Institute of Molecular and Cell Biology, Warsaw, Poland

Roles: Methodology

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Michał Mazur

1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland

Roles: Investigation

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Krzysztof Kolmus

1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland

Roles: Formal analysis

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Krzysztof Goryca

3Department of Genetics, Maria Skłodowska-Curie National Research Institute of Oncology, Warsaw, Poland

Roles: Formal analysis

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Michalina Dąbrowska

3Department of Genetics, Maria Skłodowska-Curie National Research Institute of Oncology, Warsaw, Poland

Roles: Methodology

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Agnieszka Paziewska

4Department of Gastroenterology, Hepatology and Clinical Oncology, Medical Center for Postgraduate Education, Warsaw, Poland

Roles: Methodology

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Michał Mikula

3Department of Genetics, Maria Skłodowska-Curie National Research Institute of Oncology, Warsaw, Poland

Roles: Resources, Data curation

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Marta Miączyńska

1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland

Roles: Conceptualization, Resources, Supervision, Funding acquisition, Writing—original draft, review, and editing

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ORCID record for Marta Miączyńska
For correspondence: miaczynska@iimcb.gov.pl jcendrowski@iimcb.gov.pl

Published 30 March 2022. DOI: 10.26508/lsa.202101239

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ESCRT-I controls lysosomal degradation and MiT-TFE signaling

Marta Wróbel, Jarosław Cendrowski, Ewelina Szymańska, Malwina Grębowicz-Maciukiewicz, Noga Budick-Harmelin, Matylda Macias, Aleksandra Szybińska, Michał Mazur, Krzysztof Kolmus, Krzysztof Goryca, Michalina Dąbrowska, Agnieszka Paziewska, Michał Mikula, Marta Miączyńska

Life Science Alliance Mar 2022, 5 (7) e202101239; DOI: 10.26508/lsa.202101239

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ESCRT-I controls lysosomal degradation and MiT-TFE signaling

Life Science Alliance Mar 2022, 5 (7) e202101239; DOI: 10.26508/lsa.202101239

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Wróbel, M., Cendrowski, J., Szymańska, E., Grębowicz-Maciukiewicz, M., Budick-Harmelin, N., Macias, M., Szybińska, A., Mazur, M., Kolmus, K., Goryca, K., Dąbrowska, M., Paziewska, A., Mikula, M., & Miączyńska, M. (2022). Correction: ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway. Life Science Alliance, 5(10), e202201537. Accessed March 22, 2023. https://doi.org/10.26508/lsa.202201537.

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ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway

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