Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Newest Articles
    • Current Issue
    • Methods & Resources
    • Archive
    • Subjects
  • Collections
  • Submit
    • Submit a Manuscript
    • Author Guidelines
    • License, Copyright, Fee
    • FAQ
    • Why submit
  • About
    • About Us
    • Editors & Staff
    • Board Members
    • Licensing and Reuse
    • Reviewer Guidelines
    • Privacy Policy
    • Advertise
    • Contact Us
    • LSA LLC
  • Alerts
  • Other Publications
    • EMBO Press
    • The EMBO Journal
    • EMBO reports
    • EMBO Molecular Medicine
    • Molecular Systems Biology
    • Rockefeller University Press
    • Journal of Cell Biology
    • Journal of Experimental Medicine
    • Journal of General Physiology
    • Cold Spring Harbor Laboratory Press
    • Genes & Development
    • Genome Research

User menu

  • My alerts

Search

  • Advanced search
Life Science Alliance
  • Other Publications
    • EMBO Press
    • The EMBO Journal
    • EMBO reports
    • EMBO Molecular Medicine
    • Molecular Systems Biology
    • Rockefeller University Press
    • Journal of Cell Biology
    • Journal of Experimental Medicine
    • Journal of General Physiology
    • Cold Spring Harbor Laboratory Press
    • Genes & Development
    • Genome Research
  • My alerts
Life Science Alliance

Advanced Search

  • Home
  • Articles
    • Newest Articles
    • Current Issue
    • Methods & Resources
    • Archive
    • Subjects
  • Collections
  • Submit
    • Submit a Manuscript
    • Author Guidelines
    • License, Copyright, Fee
    • FAQ
    • Why submit
  • About
    • About Us
    • Editors & Staff
    • Board Members
    • Licensing and Reuse
    • Reviewer Guidelines
    • Privacy Policy
    • Advertise
    • Contact Us
    • LSA LLC
  • Alerts
  • Follow lsa Template on Twitter
Research Article
Transparent Process
Open Access

ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway

View ORCID ProfileMarta Wróbel, View ORCID ProfileJarosław Cendrowski  Correspondence email, View ORCID ProfileEwelina Szymańska, View ORCID ProfileMalwina Grębowicz-Maciukiewicz, Noga Budick-Harmelin, Matylda Macias, Aleksandra Szybińska, Michał Mazur, View ORCID ProfileKrzysztof Kolmus, Krzysztof Goryca, Michalina Dąbrowska, Agnieszka Paziewska, Michał Mikula, View ORCID ProfileMarta Miączyńska  Correspondence email
Marta Wróbel
1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland
Roles: Conceptualization, Data curation, Formal analysis, Validation, Investigation, Visualization, Methodology, Writing—original draft, This author and J Cendrowski contributed equally
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Marta Wróbel
Jarosław Cendrowski
1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland
Roles: Conceptualization, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Visualization, Project administration, Writing—original draft, review, and editing, This author and M Wrobel contributed equally
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Jarosław Cendrowski
  • For correspondence: miaczynska@iimcb.gov.pl jcendrowski@iimcb.gov.pl
Ewelina Szymańska
1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland
Roles: Validation, Investigation, Visualization
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Ewelina Szymańska
Malwina Grębowicz-Maciukiewicz
1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland
Roles: Investigation, Visualization
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Malwina Grębowicz-Maciukiewicz
Noga Budick-Harmelin
1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland
Roles: Investigation
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Matylda Macias
2Microscopy and Cytometry Facility, International Institute of Molecular and Cell Biology, Warsaw, Poland
Roles: Visualization, Methodology
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Aleksandra Szybińska
2Microscopy and Cytometry Facility, International Institute of Molecular and Cell Biology, Warsaw, Poland
Roles: Methodology
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michał Mazur
1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland
Roles: Investigation
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Krzysztof Kolmus
1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland
Roles: Formal analysis
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Krzysztof Kolmus
Krzysztof Goryca
3Department of Genetics, Maria Skłodowska-Curie National Research Institute of Oncology, Warsaw, Poland
Roles: Formal analysis
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michalina Dąbrowska
3Department of Genetics, Maria Skłodowska-Curie National Research Institute of Oncology, Warsaw, Poland
Roles: Methodology
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Agnieszka Paziewska
4Department of Gastroenterology, Hepatology and Clinical Oncology, Medical Center for Postgraduate Education, Warsaw, Poland
Roles: Methodology
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michał Mikula
3Department of Genetics, Maria Skłodowska-Curie National Research Institute of Oncology, Warsaw, Poland
Roles: Resources, Data curation
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Marta Miączyńska
1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland
Roles: Conceptualization, Resources, Supervision, Funding acquisition, Writing—original draft, review, and editing
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Marta Miączyńska
  • For correspondence: miaczynska@iimcb.gov.pl jcendrowski@iimcb.gov.pl
Published 30 March 2022. DOI: 10.26508/lsa.202101239
  • Article
  • Figures & Data
  • Info
  • Metrics
  • Reviewer Comments
  • PDF
Loading

Article Information

vol. 5 no. 7 e202101239
DOI 
https://doi.org/10.26508/lsa.202101239
PubMed 
35354596

Published By 
Life Science Alliance
Online ISSN 
2575-1077
History 
  • Received September 21, 2021
  • Revision received March 14, 2022
  • Accepted March 15, 2022
  • Published online March 30, 2022.

Copyright & Usage 
© 2022 Wróbel et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

Author Information

  1. Marta Wróbel, Conceptualization, Data curation, Formal analysis, Validation, Investigation, Visualization, Methodology, Writing—original draft, This author and J Cendrowski contributed equally1,*,
  2. Jarosław Cendrowski, Conceptualization, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Visualization, Project administration, Writing—original draft, review, and editing, This author and M Wrobel contributed equally1,*⇑,
  3. Ewelina Szymańska, Validation, Investigation, Visualization1,
  4. Malwina Grębowicz-Maciukiewicz, Investigation, Visualization1,
  5. Noga Budick-Harmelin, Investigation1,
  6. Matylda Macias, Visualization, Methodology2,
  7. Aleksandra Szybińska, Methodology2,
  8. Michał Mazur, Investigation1,
  9. Krzysztof Kolmus, Formal analysis1,
  10. Krzysztof Goryca, Formal analysis3,
  11. Michalina Dąbrowska, Methodology3,
  12. Agnieszka Paziewska, Methodology4,
  13. Michał Mikula, Resources, Data curation3 and
  14. Marta Miączyńska, Conceptualization, Resources, Supervision, Funding acquisition, Writing—original draft, review, and editing1⇑
  1. 1Laboratory of Cell Biology, International Institute of Molecular and Cell Biology, Warsaw, Poland
  2. 2Microscopy and Cytometry Facility, International Institute of Molecular and Cell Biology, Warsaw, Poland
  3. 3Department of Genetics, Maria Skłodowska-Curie National Research Institute of Oncology, Warsaw, Poland
  4. 4Department of Gastroenterology, Hepatology and Clinical Oncology, Medical Center for Postgraduate Education, Warsaw, Poland
  1. Correspondence: miaczynska{at}iimcb.gov.pl; jcendrowski{at}iimcb.gov.pl
  1. ↵* Marta Wróbel and Jarosław Cendrowski contributed equally to this work.

  • Noga Budick-Harmelin’s present address is The Shmunis School of Biomedicine and Cancer Research, the George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.

  • Krzysztof Goryca’s present address is Centre of New Technologies, Warsaw, Poland.

  • Agnieszka Paziewska’s present address is Department of Neuroendocrinology, Centre of Postgraduate Medical Education, Warsaw, Poland and Faculty of Medical and Health Sciences, Institute of Health Sciences, Siedlce University of Natural Sciences and Humanities, Siedlce, Poland.

View Full Text

Funding

  • Foundation for Polish Science, TEAM

    POIR.04.04.00-00-20CE/16–00
    M Miaczynska
  • Foundation for Polish Science, HOMING

    POIR.04.04.00-00-1C54/16-00
    J Cendrowski
  • National Science Centre, Opus

    2020/37/B/NZ3/02991
    E Szymańska, M Grębowicz-Maciukiewicz
PreviousNext
Back to top
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Life Science Alliance.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway
(Your Name) has sent you a message from Life Science Alliance
(Your Name) thought you would like to see the Life Science Alliance web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
ESCRT-I controls lysosomal degradation and MiT-TFE signaling
Marta Wróbel, Jarosław Cendrowski, Ewelina Szymańska, Malwina Grębowicz-Maciukiewicz, Noga Budick-Harmelin, Matylda Macias, Aleksandra Szybińska, Michał Mazur, Krzysztof Kolmus, Krzysztof Goryca, Michalina Dąbrowska, Agnieszka Paziewska, Michał Mikula, Marta Miączyńska
Life Science Alliance Mar 2022, 5 (7) e202101239; DOI: 10.26508/lsa.202101239

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
ESCRT-I controls lysosomal degradation and MiT-TFE signaling
Marta Wróbel, Jarosław Cendrowski, Ewelina Szymańska, Malwina Grębowicz-Maciukiewicz, Noga Budick-Harmelin, Matylda Macias, Aleksandra Szybińska, Michał Mazur, Krzysztof Kolmus, Krzysztof Goryca, Michalina Dąbrowska, Agnieszka Paziewska, Michał Mikula, Marta Miączyńska
Life Science Alliance Mar 2022, 5 (7) e202101239; DOI: 10.26508/lsa.202101239
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
Issue Cover

In this Issue

Volume 5, No. 7
July 2022
  • Table of Contents
  • Cover (PDF)
  • About the Cover
  • Masthead (PDF)
Advertisement

Jump to section

  • Article
    • Abstract
    • Introduction
    • Results
    • Discussion
    • Materials and Methods
    • Data Availability
    • Acknowledgments
    • References
  • Figures & Data
  • Info
  • Metrics
  • Reviewer Comments
  • PDF

Subjects

  • Cancer
  • Cell Biology
  • Metabolism

Related Articles

  • Wróbel, M., Cendrowski, J., Szymańska, E., Grębowicz-Maciukiewicz, M., Budick-Harmelin, N., Macias, M., Szybińska, A., Mazur, M., Kolmus, K., Goryca, K., Dąbrowska, M., Paziewska, A., Mikula, M., & Miączyńska, M. (2022). Correction: ESCRT-I fuels lysosomal degradation to restrict TFEB/TFE3 signaling via the Rag-mTORC1 pathway. Life Science Alliance, 5(10), e202201537. Accessed March 28, 2023. https://doi.org/10.26508/lsa.202201537.

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Dimeric mtHsp60 with Inactive ATPase Activity
  • Mechanics of cardiac pacemaker cell development
  • Interaction hub for telomerase function
Show more Research Article

Similar Articles

EMBO Press LogoRockefeller University Press LogoCold Spring Harbor Logo

Content

  • Home
  • Newest Articles
  • Current Issue
  • Archive
  • Subject Collections

For Authors

  • Submit a Manuscript
  • Author Guidelines
  • License, copyright, Fee

Other Services

  • Alerts
  • Twitter
  • RSS Feeds

More Information

  • Editors & Staff
  • Reviewer Guidelines
  • Feedback
  • Licensing and Reuse
  • Privacy Policy

ISSN: 2575-1077
© 2023 Life Science Alliance LLC

Life Science Alliance is registered as a trademark in the U.S. Patent and Trade Mark Office and in the European Union Intellectual Property Office.