Research Article
Open Access
LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity
View ORCID ProfileGiuseppe Bombaci, View ORCID ProfileMayuresh Anant Sarangdhar, View ORCID ProfileNicola Andina, Aubry Tardivel, View ORCID ProfileEric Chi-Wang Yu, View ORCID ProfileGillian M Mackie, View ORCID ProfileMatthew Pugh, View ORCID ProfileVedat Burak Ozan, Yara Banz, View ORCID ProfileThibaud Spinetti, View ORCID ProfileCedric Hirzel, Esther Youd, View ORCID ProfileJoerg C Schefold, View ORCID ProfileGraham Taylor, Amiq Gazdhar, Nicolas Bonadies, Anne Angelillo-Scherrer, View ORCID ProfilePascal Schneider, View ORCID ProfileKendle M Maslowski, View ORCID ProfileRamanjaneyulu Allam Correspondence email
Giuseppe Bombaci
1Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
2Department for BioMedical Research, University of Bern, Bern, Switzerland
3Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland
Roles: Data curation, Formal analysis, Validation, Investigation, Methodology, Writing—original draft
Mayuresh Anant Sarangdhar
1Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
2Department for BioMedical Research, University of Bern, Bern, Switzerland
Roles: Data curation, Formal analysis, Validation, Investigation, Methodology, Writing—original draft
Nicola Andina
1Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
2Department for BioMedical Research, University of Bern, Bern, Switzerland
Roles: Data curation, Investigation
Aubry Tardivel
1Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
2Department for BioMedical Research, University of Bern, Bern, Switzerland
Roles: Formal analysis, Investigation, Methodology
Eric Chi-Wang Yu
4Department of Biochemistry, University of Lausanne, Lausanne, Switzerland
Roles: Investigation, Methodology
Gillian M Mackie
5Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK
6Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Roles: Data curation, Investigation, Methodology
Matthew Pugh
5Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK
Roles: Data curation, Formal analysis, Methodology
Vedat Burak Ozan
2Department for BioMedical Research, University of Bern, Bern, Switzerland
11Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
Roles: Investigation, Methodology
Yara Banz
7Institute of Pathology, University of Bern, Bern, Switzerland
Roles: Formal analysis, Methodology
Thibaud Spinetti
8Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
Roles: Resources, Data curation, Formal analysis, Validation, Investigation, Methodology, Writing—original draft, review, and editing
Cedric Hirzel
9Department of Infectious Diseases, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
Roles: Data curation, Validation, Investigation, Methodology
Esther Youd
10School of Medicine, Dentistry and Nursing, Forensic Medicine and Science. University of Glasgow, Scotland, UK
Roles: Resources, Data curation
Joerg C Schefold
8Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
Roles: Resources, Formal analysis, Writing—original draft, review, and editing
Graham Taylor
5Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK
Roles: Resources, Formal analysis
Amiq Gazdhar
2Department for BioMedical Research, University of Bern, Bern, Switzerland
11Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
Roles: Formal analysis, Investigation, Methodology
Nicolas Bonadies
1Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
2Department for BioMedical Research, University of Bern, Bern, Switzerland
Roles: Resources, Validation, Investigation, Methodology
Anne Angelillo-Scherrer
1Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
2Department for BioMedical Research, University of Bern, Bern, Switzerland
Roles: Resources, Methodology
Pascal Schneider
4Department of Biochemistry, University of Lausanne, Lausanne, Switzerland
Roles: Resources, Methodology, Writing—original draft
Kendle M Maslowski
5Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK
6Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Roles: Resources, Data curation, Formal analysis, Investigation, Methodology, Writing—original draft, review, and editing
Ramanjaneyulu Allam
1Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
2Department for BioMedical Research, University of Bern, Bern, Switzerland
Roles: Conceptualization, Resources, Data curation, Formal analysis, Supervision, Funding acquisition, Validation, Investigation, Visualization, Methodology, Project administration, Writing—original draft, review, and editing
Published 7 March 2022. DOI: 10.26508/lsa.202101226
RNH1 inhibits inflammasome activation
Giuseppe Bombaci, Mayuresh Anant Sarangdhar, Nicola Andina, Aubry Tardivel, Eric Chi-Wang Yu, Gillian M Mackie, Matthew Pugh, Vedat Burak Ozan, Yara Banz, Thibaud Spinetti, Cedric Hirzel, Esther Youd, Joerg C Schefold, Graham Taylor, Amiq Gazdhar, Nicolas Bonadies, Anne Angelillo-Scherrer, Pascal Schneider, Kendle M Maslowski, Ramanjaneyulu Allam
Life Science Alliance Mar 2022, 5 (6) e202101226; DOI: 10.26508/lsa.202101226
RNH1 inhibits inflammasome activation
Giuseppe Bombaci, Mayuresh Anant Sarangdhar, Nicola Andina, Aubry Tardivel, Eric Chi-Wang Yu, Gillian M Mackie, Matthew Pugh, Vedat Burak Ozan, Yara Banz, Thibaud Spinetti, Cedric Hirzel, Esther Youd, Joerg C Schefold, Graham Taylor, Amiq Gazdhar, Nicolas Bonadies, Anne Angelillo-Scherrer, Pascal Schneider, Kendle M Maslowski, Ramanjaneyulu Allam
Life Science Alliance Mar 2022, 5 (6) e202101226; DOI: 10.26508/lsa.202101226
In this Issue
Volume 5, No. 6
June 2022
Advertisement
Jump to section
Subjects
Related Articles
- No related articles found.