Research Article
Open Access
Single serine on TSC2 exerts biased control over mTORC1 activation mediated by ERK1/2 but not Akt
Brittany L Dunkerly-Eyring, Shi Pan, Miguel Pinilla-Vera, Desirae McKoy, Sumita Mishra, Maria I Grajeda Martinez, Christian U Oeing, Mark J Ranek, View ORCID ProfileDavid A Kass Correspondence email
Brittany L Dunkerly-Eyring
1Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
2Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Roles: Data curation, Formal analysis, Investigation, Writing—original draft
Shi Pan
1Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Roles: Data curation, Formal analysis
Miguel Pinilla-Vera
1Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Roles: Formal analysis, Investigation
Desirae McKoy
1Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Roles: Investigation
Sumita Mishra
1Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Roles: Formal analysis, Investigation
Maria I Grajeda Martinez
1Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Roles: Investigation
Christian U Oeing
1Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Roles: Formal analysis, Investigation
Mark J Ranek
1Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
2Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Roles: Resources, Methodology
David A Kass
1Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
2Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Roles: Conceptualization, Data curation, Formal analysis, Supervision, Funding acquisition, Investigation, Project administration, Writing—review and editing
Published 14 March 2022. DOI: 10.26508/lsa.202101169
Biased control of mTORC1 by TSC2-S1364
Brittany L Dunkerly-Eyring, Shi Pan, Miguel Pinilla-Vera, Desirae McKoy, Sumita Mishra, Maria I Grajeda Martinez, Christian U Oeing, Mark J Ranek, David A Kass
Life Science Alliance Mar 2022, 5 (6) e202101169; DOI: 10.26508/lsa.202101169
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Volume 5, No. 6
June 2022
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