Research Article
Open Access
Age-related differences in immune dynamics during SARS-CoV-2 infection in rhesus macaques
View ORCID ProfileEmily Speranza, Jyothi N Purushotham, View ORCID ProfileJulia R Port, Benjamin Schwarz, View ORCID ProfileMeaghan Flagg, View ORCID ProfileBrandi N Williamson, Friederike Feldmann, Manmeet Singh, View ORCID ProfileLizzette Pérez-Pérez, Gail L Sturdevant, Lydia M Roberts, Aaron Carmody, Jonathan E Schulz, View ORCID ProfileNeeltje van Doremalen, Atsushi Okumura, Jamie Lovaglio, View ORCID ProfilePatrick W Hanley, Carl Shaia, Ronald N Germain, Sonja M Best, Vincent J Munster, Catharine M Bosio, View ORCID ProfileEmmie de Wit Correspondence email
Emily Speranza
1Laboratory of Immune System Biology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA
Roles: Conceptualization, Resources, Data curation, Formal analysis, Investigation, Visualization, Methodology, Writing—original draft, review, and editing
Jyothi N Purushotham
2Laboratory of Virology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
3The Jenner Institute, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
Roles: Conceptualization, Resources, Data curation, Formal analysis, Investigation, Visualization, Methodology, Writing—original draft, review, and editing
Julia R Port
2Laboratory of Virology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Data curation, Formal analysis, Investigation, Methodology, Writing—review and editing
Benjamin Schwarz
4Laboratory of Bacteriology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Resources, Data curation, Formal analysis, Investigation, Methodology, Writing—review and editing
Meaghan Flagg
2Laboratory of Virology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Data curation, Formal analysis, Investigation, Visualization, Methodology, Writing—review and editing
Brandi N Williamson
2Laboratory of Virology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Investigation, Methodology, Writing—review and editing
Friederike Feldmann
5Rocky Mountain Veterinary Branch, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Investigation, Methodology, Writing—review and editing
Manmeet Singh
2Laboratory of Virology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Investigation, Methodology, Writing—review and editing
Lizzette Pérez-Pérez
2Laboratory of Virology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Investigation, Methodology, Writing—review and editing
Gail L Sturdevant
2Laboratory of Virology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Investigation, Methodology, Writing—review and editing
Lydia M Roberts
4Laboratory of Bacteriology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Investigation, Methodology, Writing—review and editing
Aaron Carmody
6Research Technologies Branch, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Investigation, Methodology, Writing—review and editing
Jonathan E Schulz
2Laboratory of Virology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Investigation, Methodology, Writing—review and editing
Neeltje van Doremalen
2Laboratory of Virology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Investigation, Methodology, Writing—review and editing
Atsushi Okumura
2Laboratory of Virology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Investigation, Methodology, Writing—review and editing
Jamie Lovaglio
5Rocky Mountain Veterinary Branch, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Investigation, Methodology, Writing—review and editing
Patrick W Hanley
5Rocky Mountain Veterinary Branch, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Investigation, Methodology, Writing—review and editing
Carl Shaia
5Rocky Mountain Veterinary Branch, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Formal analysis, Investigation, Methodology, Writing—review and editing
Ronald N Germain
1Laboratory of Immune System Biology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA
Roles: Resources, Investigation, Methodology, Writing—review and editing
Sonja M Best
2Laboratory of Virology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Resources, Methodology, Writing—review and editing
Vincent J Munster
2Laboratory of Virology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Resources, Investigation, Methodology, Writing—review and editing
Catharine M Bosio
4Laboratory of Bacteriology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Resources, Methodology, Writing—review and editing
Emmie de Wit
2Laboratory of Virology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Hamilton, MT, USA
Roles: Conceptualization, Resources, Formal analysis, Supervision, Validation, Investigation, Methodology, Writing—original draft, review, and editing
Published 17 January 2022. DOI: 10.26508/lsa.202101314
SARS-CoV-2 age-related immune dynamics
Emily Speranza, Jyothi N Purushotham, Julia R Port, Benjamin Schwarz, Meaghan Flagg, Brandi N Williamson, Friederike Feldmann, Manmeet Singh, Lizzette Pérez-Pérez, Gail L Sturdevant, Lydia M Roberts, Aaron Carmody, Jonathan E Schulz, Neeltje van Doremalen, Atsushi Okumura, Jamie Lovaglio, Patrick W Hanley, Carl Shaia, Ronald N Germain, Sonja M Best, Vincent J Munster, Catharine M Bosio, Emmie de Wit
Life Science Alliance Jan 2022, 5 (4) e202101314; DOI: 10.26508/lsa.202101314
SARS-CoV-2 age-related immune dynamics
Emily Speranza, Jyothi N Purushotham, Julia R Port, Benjamin Schwarz, Meaghan Flagg, Brandi N Williamson, Friederike Feldmann, Manmeet Singh, Lizzette Pérez-Pérez, Gail L Sturdevant, Lydia M Roberts, Aaron Carmody, Jonathan E Schulz, Neeltje van Doremalen, Atsushi Okumura, Jamie Lovaglio, Patrick W Hanley, Carl Shaia, Ronald N Germain, Sonja M Best, Vincent J Munster, Catharine M Bosio, Emmie de Wit
Life Science Alliance Jan 2022, 5 (4) e202101314; DOI: 10.26508/lsa.202101314
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Volume 5, No. 4
April 2022
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