Research Article
Open Access
Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells
View ORCID ProfileJohanna Grinat, Frauke Kosel, View ORCID ProfileNeha Goveas, View ORCID ProfileAndrea Kranz, View ORCID ProfileDimitra Alexopoulou, View ORCID ProfileKlaus Rajewsky, Michael Sigal, A Francis Stewart, View ORCID ProfileJulian Heuberger Correspondence email
Johanna Grinat
1Cancer Research Program, Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Society, Berlin, Germany
Roles: Formal analysis, Validation, Investigation, Visualization, Methodology, Writing—original draft, review, and editing
Frauke Kosel
1Cancer Research Program, Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Society, Berlin, Germany
Roles: Investigation, Methodology
Neha Goveas
2Genomics, Center for Molecular and Cellular Bioengineering, Biotechnology Center, Technische Universität Dresden, Dresden, Germany
Roles: Conducted the Paneth cell sort
Andrea Kranz
2Genomics, Center for Molecular and Cellular Bioengineering, Biotechnology Center, Technische Universität Dresden, Dresden, Germany
Roles: Conducted the Paneth cell sort
Dimitra Alexopoulou
3DRESDEN-concept Genome Center, Center for Molecular and Cellular Bioengineering, Technische Universität Dresden, Dresden, Germany
Roles: Performed bioinformatic analyses
Klaus Rajewsky
1Cancer Research Program, Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Society, Berlin, Germany
Roles: Resources
Michael Sigal
4Medical Department, Division of Gastroenterology and Hepatology, Charité University Medicine, Berlin, Germany
5Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany
Roles: Resources
A Francis Stewart
2Genomics, Center for Molecular and Cellular Bioengineering, Biotechnology Center, Technische Universität Dresden, Dresden, Germany
6Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
Roles: Resources
Julian Heuberger
4Medical Department, Division of Gastroenterology and Hepatology, Charité University Medicine, Berlin, Germany
5Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany
Roles: Conceptualization, Formal analysis, Supervision, Validation, Investigation, Visualization, Methodology, Project administration, Writing—original draft, review, and editing
Published 21 January 2022. DOI: 10.26508/lsa.202101187
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Epigenetic control of secretory cell fates
Johanna Grinat, Frauke Kosel, Neha Goveas, Andrea Kranz, Dimitra Alexopoulou, Klaus Rajewsky, Michael Sigal, A Francis Stewart, Julian Heuberger
Life Science Alliance Jan 2022, 5 (4) e202101187; DOI: 10.26508/lsa.202101187
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Volume 5, No. 4
April 2022
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