Sumoylation of Cas9 at lysine 848 regulates protein stability and DNA binding

Tunahan Ergünay; Özgecan Ayhan; Arda B Celen; Panagiota Georgiadou; Emre Pekbilir; Yusuf T Abaci; Duygu Yesildag; Mandy Rettel; Ulduz Sobhiafshar; Anna Ogmen; NC Tolga Emre; Umut Sahin

doi:10.26508/lsa.202101078

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Sumoylation of Cas9 at lysine 848 regulates protein stability and DNA binding

View ORCID ProfileTunahan Ergünay, View ORCID ProfileÖzgecan Ayhan, View ORCID ProfileArda B Celen, Panagiota Georgiadou, View ORCID ProfileEmre Pekbilir, Yusuf T Abaci, Duygu Yesildag, Mandy Rettel, Ulduz Sobhiafshar, Anna Ogmen, View ORCID ProfileNC Tolga Emre, View ORCID ProfileUmut Sahin Correspondence email

Tunahan Ergünay

1Department of Molecular Biology and Genetics, Bogazici University, Center for Life Sciences and Technologies, Istanbul, Turkey

Roles: Data curation, Formal analysis, Investigation, Methodology

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ORCID record for Tunahan Ergünay

Özgecan Ayhan

1Department of Molecular Biology and Genetics, Bogazici University, Center for Life Sciences and Technologies, Istanbul, Turkey

Roles: Data curation, Formal analysis, Investigation, Methodology

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Arda B Celen

1Department of Molecular Biology and Genetics, Bogazici University, Center for Life Sciences and Technologies, Istanbul, Turkey

Roles: Data curation, Formal analysis, Investigation, Methodology, Writing—original draft, and editing

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Panagiota Georgiadou

1Department of Molecular Biology and Genetics, Bogazici University, Center for Life Sciences and Technologies, Istanbul, Turkey

Roles: Formal analysis, Investigation, Methodology

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Emre Pekbilir

1Department of Molecular Biology and Genetics, Bogazici University, Center for Life Sciences and Technologies, Istanbul, Turkey

Roles: Data curation, Software, Formal analysis, Investigation, Methodology

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Yusuf T Abaci

1Department of Molecular Biology and Genetics, Bogazici University, Center for Life Sciences and Technologies, Istanbul, Turkey

Roles: Formal analysis, Investigation, Methodology

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Duygu Yesildag

1Department of Molecular Biology and Genetics, Bogazici University, Center for Life Sciences and Technologies, Istanbul, Turkey

Roles: Formal analysis, Investigation, Methodology

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Mandy Rettel

2European Molecular Biology Laboratory, Proteomics Core Facility, Heidelberg, Germany

Roles: Data curation, Software, Formal analysis, Investigation, Methodology

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Ulduz Sobhiafshar

1Department of Molecular Biology and Genetics, Bogazici University, Center for Life Sciences and Technologies, Istanbul, Turkey

Roles: Investigation, Methodology

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Anna Ogmen

1Department of Molecular Biology and Genetics, Bogazici University, Center for Life Sciences and Technologies, Istanbul, Turkey

Roles: Resources, Investigation

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NC Tolga Emre

1Department of Molecular Biology and Genetics, Bogazici University, Center for Life Sciences and Technologies, Istanbul, Turkey

Roles: Resources, Formal analysis, Investigation

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Umut Sahin

1Department of Molecular Biology and Genetics, Bogazici University, Center for Life Sciences and Technologies, Istanbul, Turkey

Roles: Conceptualization, Data curation, Formal analysis, Supervision, Funding acquisition, Methodology, Writing—original draft and editing, Project administration

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For correspondence: umut.sahin@boun.edu.tr

Published 12 January 2022. DOI: 10.26508/lsa.202101078

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Sumoylation and ubiquitylation of Cas9

Tunahan Ergünay, Özgecan Ayhan, Arda B Celen, Panagiota Georgiadou, Emre Pekbilir, Yusuf T Abaci, Duygu Yesildag, Mandy Rettel, Ulduz Sobhiafshar, Anna Ogmen, NC Tolga Emre, Umut Sahin

Life Science Alliance Jan 2022, 5 (4) e202101078; DOI: 10.26508/lsa.202101078

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Sumoylation and ubiquitylation of Cas9

Tunahan Ergünay, Özgecan Ayhan, Arda B Celen, Panagiota Georgiadou, Emre Pekbilir, Yusuf T Abaci, Duygu Yesildag, Mandy Rettel, Ulduz Sobhiafshar, Anna Ogmen, NC Tolga Emre, Umut Sahin

Life Science Alliance Jan 2022, 5 (4) e202101078; DOI: 10.26508/lsa.202101078

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